DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1441 and CG34342

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	154/536 - (28%)
Similarity:	260/536 - (48%)	Gaps:	40/536 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VYEKDDRGTIGEIDDNEVDRIA-------------ECFKGRSLFITGGTGFLGKVLVEKLLRSCG 59
            ::::...||    ..|.||.||             :.:...::.|||||||:||||.||||||.
  Fly    41 LFQEASSGT----RTNSVDGIAAPFTAAVSATPVTDFYSNATVLITGGTGFVGKVLTEKLLRSF- 100

  Fly    60 GLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQVKQMRGEE-HILQQVVAIAGDVLSPGLGISEKD 123
            ||::||:|||.|.....|||:|..|...:|:   :||.|. .:|.:|..|..|..:..|.|...|
  Fly   101 GLRKIYMLIRSKDNMSVQERLKGFFNESIFN---RMREESPQLLAKVHPIRADYSAIDLDIDSAD 162

  Fly   124 LETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRGTKYMLELALTLKHLDFFAYCSTAYCHLHVKT 188
            ...|..||.||::..|:|:|:|.|.:|:.:|..|||.:|:|.:.:|||..|.:.||.||:.:.|.
  Fly   163 RAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTKKILDLVMEMKHLKSFVHISTLYCNCNRKF 227

  Fly   189 LYEKPYDPPADPHKVMQACEWLTDDEVATIERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVIL 253
            :.|:.|:......|:||......|:.:..:...::|.:||||..||..||.||..:...:||.|.
  Fly   228 IKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIGQMPNTYTMTKKCAENLVNHRAFHMPAGIF 292

  Fly   254 RPSIVIPIWKEPIPGWTDNINGPTGLLIGAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASW-- 316
            ||.||:..:|:|.||||||:.||:||...:.:|::|.:|..:|...:.:|.|..||.::..:|
  Fly   293 RPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVRCIYGKASCKANMVPADYVVNAMIATAWDI 357

  Fly   317 -RNITAGTDKTNRVAHMTSSNDI----KVSWAEIIELGRWVIENKVPLNGVAWYPGGSMKSNYWV 376
             |.......|.:..:.:...|.:    .::|.:.:.|.|.....  |.:...|.....:..:..:
  Fly   358 ARRFKLRESKVDGKSELPVYNYVSDANNITWGQYMHLSRKGFHE--PFDKALWCFSYVIIPSKPL 420

  Fly   377 HFICMVLF--QWMPALFVDALLWILRYPPVLCRVQNRIYKGFEVFEYYANNVWNFDNSEAVKLRK 439
            |  |.:.|  ..:||..:|.:..:.....:..:...:|.:..::..::....|.|.:....:|.:
  Fly   421 H--CAIAFFLHNIPAYILDLIAMVTGQKRIYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNE 483

  Fly   440 LMNNKERRTYVIEKIELDLIDYFTNCVLCARRLILKES--DESIPAAR---RHMKVMWVVDKVYK 499
            |:..:||.........::..:||.:.:...||...|:|  |..:...|   |.|.::..:.|...
  Fly   484 LLPREERSVLQFNIATINWSEYFRSYLSGIRRYFFKDSANDNKLQQRRTIYRRMLILHTLLKTTF 548

  Fly   500 GIWIFGILYMLYRCFF 515
            |:.:...:..:|...|
  Fly   549 GLSLIMCMLRVYLRIF 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	139/462 (30%)
		FAR-N_SDR_e	35..348	CDD:187547	116/320 (36%)
		Sterile	385..475	CDD:281068	14/89 (16%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	137/456 (30%)
		FAR-N_SDR_e	78..397	CDD:187547	117/322 (36%)
		Sterile	429..519	CDD:281068	14/89 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466776
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	9.000