DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1441 and Far2

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_006237759.1	Gene:	Far2 / 500368	RGDID:	1565966	Length:	515	Species:	Rattus norvegicus

Alignment Length:	511	Identity:	169/511 - (33%)
Similarity:	271/511 - (53%)	Gaps:	38/511 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQV 92
            ||..:..:|:.|||.||||||||:|||.|:...||.||:|:|||.|:..|||:..|..:.||::|
  Rat     4 IAAFYSNKSILITGATGFLGKVLMEKLFRTSPHLKVIYILVRPKSGQTLQERVFQILNSKLFERV 68

  Fly    93 KQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRG 157
            |::....|  :::..|:.|:......||::|::.|....:||:|||||||||..||.||.:|...
  Rat    69 KEVCPNVH--EKIRPISADLNQRDFAISKEDMQELLSCTNIVFHCAATVRFDAHLREAVQLNVTA 131

  Fly   158 TKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDPPADPHKVMQACEWLTDDEVATIERKV 222
            |:.:|.:|..:..|:.|.:.|||:.:.::..:.|..|..|.:|.|::.:.|||.|..:..|..|:
  Rat   132 TQQLLLMASEMPKLEAFIHISTAFSNCNLSHIDEVIYPCPVEPRKIIDSMEWLDDSIIEEITPKL 196

  Fly   223 LGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLIGAGKGV 287
            :|..||||.|||:|.|.:|.::...|...|:|||||...|:||.|||.||:|||:||:|..|||.
  Rat   197 IGDRPNTYTYTKALGEVVVQQESGNLNVAIVRPSIVGATWQEPFPGWVDNLNGPSGLIIATGKGF 261

  Fly   288 IRTMYCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNRVAHMTSSNDIKVSWAEIIELGRWV 352
            :|::........|.:|||..||..:...|.. .....|:..:.|.||.|....:|   .|:|..|
  Rat   262 LRSIKATPMAVADLIPVDTVVNLTIAVGWYT-AVHRPKSTLIYHSTSGNLNPCNW---YEMGLQV 322

  Fly   353 IE--NKVPLNGVAWYPGGSMKSN-----YWVHFICMVLFQWMPALFVDALLWILRYPPVLCRVQN 410
            :.  .|:|.......|.....:|     ||     ..:..|.||:..|..|.:....|.:.::.|
  Rat   323 LATVEKIPFESAFRRPNADFTTNNFTTQYW-----NTVSHWAPAIIYDFYLRLTGRKPRMLKLMN 382

  Fly   411 RIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCARRLILK 475
            |:.|...:.||:.|:.|.:..:....|...::.:::|.:..:..:|:.::|..|.||..::.:||
  Rat   383 RLLKTISMLEYFINHSWEWSTNNTEMLLSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLK 447

  Fly   476 ESDESIPAARRHMK---------------VMWVV----DKVYKGIWIFGILYMLYR 512
            |....||.|::|:|               ::|.:    .::.:.||.| |:...|:
  Rat   448 EDLAGIPKAKQHLKRLRNIHYLFNTALFLIIWRLLIARSQMARNIWFF-IVSFCYK 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	152/442 (34%)
		FAR-N_SDR_e	35..348	CDD:187547	124/312 (40%)
		Sterile	385..475	CDD:281068	20/89 (22%)
Far2	XP_006237759.1	FAR-N_SDR_e	11..318	CDD:187547	124/312 (40%)
Far2	XP_006237759.1	Sterile	357..447	CDD:397244	20/89 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351508
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.760