DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1441 and far1

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	515	Identity:	177/515 - (34%)
Similarity:	283/515 - (54%)	Gaps:	42/515 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQV 92
            |.|.:.|:::.|||.|||:||||:|||||||.|:|..|:|:|||.|:.|..||.|:....|||::
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    93 KQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRG 157
            ::  .:.....::|||..|:..|.|.:|.:|.|||...:::|:|||||:||:|||::|:.:|...
Zfish    69 RE--DQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLA 131

  Fly   158 TKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDPPADPHKVMQACEWLTDDEVATIERKV 222
            |:.|:.||..:|||:.|.:.||||.:...:.:.|..|.||.|..|::...||:.|..|:.:..::
Zfish   132 TQKMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRL 196

  Fly   223 LGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLIGAGKGV 287
            ||..||||.|||:|||.||.::...|...|:|||||...||||.|||.||.|||:|:.|.||||:
Zfish   197 LGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGI 261

  Fly   288 IRTMYCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNR-----VAHMTSSNDIKVSWAEIIE 347
            :|||..:::...|.:||||.:|..|.|:|   .:|:.:..|     |.:.|:.......|.|:
Zfish   262 LRTMRASNNAVADLVPVDVVINTTLAAAW---YSGSQRHARPRSLLVYNCTTGGINPFHWGEV-- 321

  Fly   348 LGRWVIE--NKVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALLWILRYPPVLCRVQN 410
             ...||.  .:.||......|..::.:|:.::...:.:....||...|..|.:....|.:.:...
Zfish   322 -EYHVISTFKRNPLEQAFRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREPRMMKTIT 385

  Fly   411 RIYKGFEVFEYYANN--VWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCARRLI 473
            |::|...|.||:.::  |||.||  ...|...|..::::.:..:..:|...:|..|..:..::.:
Zfish   386 RLHKAMMVLEYFTSHSWVWNTDN--VTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTKKYV 448

  Fly   474 LKESDESIPAARRHMK---------------VMWVV----DKVYKGIWIFGILYMLYRCF 514
            |.|....:||||:|:.               ::|.:    .::.:.||.|    ::..||
Zfish   449 LNEELSGLPAARKHLNKLRNIRYTFNTVLVVLIWRIFIARSQMARNIWYF----VVSLCF 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	163/444 (37%)
		FAR-N_SDR_e	35..348	CDD:187547	135/317 (43%)
		Sterile	385..475	CDD:281068	20/91 (22%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	137/329 (42%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	20/91 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593277
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960