DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1441 and CG10096

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	153/500 - (30%)
Similarity:	255/500 - (51%)	Gaps:	38/500 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERI----KD-IFQNVLFDQ 91
            :|.:::|:|||:||||||.:.|||.:. .:||||:|:|.|:|::.:||.    || :|.|:
  Fly     9 YKDKTVFLTGGSGFLGKVTIAKLLCTT-EVKRIYVLLRAKRGQEMRERCAAWDKDPVFGNL---- 68

  Fly    92 VKQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTR 156
               |:.....|::||...||...|.||:|..|.:.|..||.||.|.||||||.|||..|:.:|||
  Fly    69 ---MKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTR 130

  Fly   157 GTKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDP----PADPHKVMQACEWLTDDEVAT 217
            .|:.|::||..:.||:.|.:.||||.:..|:.:.|:.|..    ||:  |:::..|.::.:.:..
  Fly   131 ATRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAE--KILELLESISPELLDK 193

  Fly   218 IERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLIG 282
            :...::|..||||.|||:|.|.::.::.::||..|.||.::|..:|||:|||.||:.||..:|.|
  Fly   194 MAPALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYG 258

  Fly   283 AGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASW---RNITAGTDKTNRVAHMTSSNDIKVSWAE 344
            |..|::.....|.......:|||..||.:|..:|   |:.:........:.:.|.:||..::|..
  Fly   259 AAFGILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTARDTSIKLSPEPPIYNFTPNNDNLITWGG 323

  Fly   345 IIELGRWVIENKVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALLWILRYPPVLCRVQ 409
            ..:... .:....||..:.|.|.....:..|:.....:.:..:|...:|..|.:....|.:.::.
  Fly   324 FRDKAA-RLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLY 387

  Fly   410 NRIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCARRLIL 474
            ::|:|..::...:....|:||.....||...|:.::::.|......:|..|||...:...|..:.
  Fly   388 DKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQALAGVRIYLA 452

  Fly   475 KE--SDESIPAARRHMKVMWVVDKVYKGIWIFGILYMLYRCFFAG 517
            ||  ..|.:...|          |:||.   |..|:.|.:....|
  Fly   453 KEEPGQEVVERGR----------KIYKR---FEFLHRLLQFTLCG 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	141/443 (32%)
		FAR-N_SDR_e	35..348	CDD:187547	118/324 (36%)
		Sterile	385..475	CDD:281068	18/89 (20%)
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	140/442 (32%)
		FAR-N_SDR_e	12..330	CDD:187547	118/328 (36%)
		Sterile	363..453	CDD:281068	18/89 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466774
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890