DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1441 and CG8303

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001286495.1	Gene:	CG8303 / 36858	FlyBaseID:	FBgn0034143	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	164/494 - (33%)
Similarity:	257/494 - (52%)	Gaps:	28/494 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQV 92
            |.|.|..:::|:||||||||.||:|.||.:...:..||:|:|.|:..||.|||:.:.|..:|::.
  Fly    39 IPEFFAHKNIFVTGGTGFLGTVLIEALLDTHPDIGTIYVLVRGKRKFDPNERIRRLLQKPIFEKY 103

  Fly    93 KQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRG 157
                 .|..|.:||.:.|::..|..|...:.|:.|...|:::||.|||::|..|||.|:..|..|
  Fly   104 -----SEKTLSKVVPVVGELSEPNFGFGPELLQELIDRVNVIYHSAATIKFSSPLRTAIRTNLTG 163

  Fly   158 TKYMLELALTLKHLDFFAYCSTAYCHLHVKTLY-EKPYDPPADPHKVMQACEWLTDDEV--ATIE 219
            |...:|||..||.|..:.|||||:|:.:.:.|. |:.|....||:::|:..|   ||..  ...:
  Fly   164 TMRTIELAKQLKQLAAYIYCSTAFCNSNNRGLIAEEVYKSQFDPYEMMKMAE---DDSAWEDFTD 225

  Fly   220 RKVLGAI---PNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNIN-GPTGLL 280
            :|..|.|   ||||.:||:|:|.|::.:...|||.|:|||||....:.|:.||..|.| |..|.|
  Fly   226 QKCKGYIRDHPNTYTFTKNLSENLLMAEMSGLPAAIVRPSIVYGTLEHPMKGWVGNANSGHLGFL 290

  Fly   281 IGAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNR--VAHMTSSNDIKVSWA 343
            .|..||:.|||..|::...|.:|.|..:|..||..|   ..||.|..:  :.|.||.....::.|
  Fly   291 AGFVKGIFRTMCGNANAVIDIIPCDYVINSSLVMGW---YVGTRKLEQPEIIHCTSGEVNPLNLA 352

  Fly   344 EIIELGRWVIENKVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPAL--FVDALLWILRYPPVLC 406
            |...:....:|...| |...|.|...:: |.|.:.:...||..:||:  .:...|:.:..|....
  Fly   353 EFCTIINDSVERHPP-NSFVWKPVTKLR-NGWRYNLFFYLFHLLPAMVFIIPEKLFGIGMPQHTA 415

  Fly   407 RVQNRIY-KGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCAR 470
            ....|:: ||.:.|:|:.:..:.:....|:::..|:...:||.|..:..:.|..::...|::..|
  Fly   416 YEYMRVFQKGTKAFDYFLDKDFRYSLKNALRISALIPESDRRRYNFDASQCDWSEFIDRCLIGIR 480

  Fly   471 RLILKESDESIPAARRHMKVMWVVDKVYKG-IWIFGILY 508
            |...|||..:....|.:.||..|:  .|.| :.||.:||
  Fly   481 RFYFKESAVTTDWHRNYWKVFNVL--YYAGYVVIFAVLY 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	148/447 (33%)
		FAR-N_SDR_e	35..348	CDD:187547	121/321 (38%)
		Sterile	385..475	CDD:281068	18/92 (20%)
CG8303	NP_001286495.1	FAR-N_SDR_e	46..366	CDD:187547	122/330 (37%)
CG8303	NP_001286495.1	Sterile	392..485	CDD:281068	18/92 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466746
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	8.000