DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1441 and Sgp

DIOPT Version :9

Sequence 1:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001260257.1	Gene:	Sgp / 34188	FlyBaseID:	FBgn0032055	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	152/522 - (29%)
Similarity:	269/522 - (51%)	Gaps:	60/522 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERI---KD--IFQNV 87
            |.:.:|.:|:|:||||||||||::||||||. .::|:|||:||||.:..:.|.   ||  :|:.:
  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRST-DVRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68

  Fly    88 LFDQVKQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVF 152
            |       :.:...|:.|..|:||...||||:|:.|...:..:|.::.|.||::||.|||:.|:.
  Fly    69 L-------KAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALN 126

  Fly   153 MNTRGTKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYD-----PPADPHKVMQACEWLTD 212
            :|||.|:.|::||..:|.|:.|.:.|||:.:...:.:.|:.|.     |.|   ||::..|.|:.
  Fly   127 INTRATRLMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFYPEHLTCPAA---KVLEFNETLSP 188

  Fly   213 DEVATIERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPT 277
            |.:..:...::|..||||.|||:|||.::..:.::||..:.||:|::..:|||:.||.||::|..
  Fly   189 DLLDKMAPALMGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVV 253

  Fly   278 GLLIGAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNRVAHM---------- 332
            .|:.|...|::|.:|.|.......:|.|...|..|.:.|:  .|...::...:.:
  Fly   254 ALIYGNTYGILRLLYVNPKADAIIVPGDYCANVALASGWQ--VAKNSESRSSSQLAAKKPPPIYT 316

  Fly   333 ---TSSNDIKVSWAEIIELGRWVIEN-KVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVD 393
               |.||.|  ::.:.::||  :..| .:|:....|||.....:..|:..:..:.:..:|..|.|
  Fly   317 LATTKSNSI--TFGKAVKLG--IHHNHTIPVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFD 377

  Fly   394 ALLWILRYPPVLCRVQNRIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDL 458
            .||.|....|:|.|...:|::...:...:....:..|.:...:|...|:.::|..:..:...|:.
  Fly   378 LLLRIQGKKPILMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNW 442

  Fly   459 IDYFTNCVLCARRLILKESDESIPAARRHM-------------------KVMWVVDKVYKGIWIF 504
            .:|||..:...|..:.|||.:::..|::.:                   |::|::..|....:|.
  Fly   443 EEYFTRILSGMRVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLALGKIVWILYSVIANNYIR 507

  Fly   505 GI 506
            .|
  Fly   508 SI 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	141/459 (31%)
		FAR-N_SDR_e	35..348	CDD:187547	114/335 (34%)
		Sterile	385..475	CDD:281068	19/89 (21%)
Sgp	NP_001260257.1	PLN02996	1..449	CDD:215538	142/460 (31%)
		FAR-N_SDR_e	12..333	CDD:187547	114/335 (34%)
		FAR_C	367..457	CDD:176924	19/89 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466781
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900