Protein Alignment CG1441 and Far1

DIOPT Version :10

• Sequence 1: NP_610535.1
• Gene: CG1441 / 36029
• FlyBaseID: FBgn0033464
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001011933.1
• Gene: Far1 / 293173
• RGDID: 1306647
• Length: 515
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 182/519 - (35%)
• Similarity: 290/519 - (55%)
• Gaps: 54/519 - (10%)

  Fly    28 IAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQV 92
            |.|.::|:::.:||.||||||||:|||||||..:..:|:|:|.|.|:.||||:::|....|||::
  Rat     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRL 68

  Fly    93 KQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRG 157
            :....:  ..|:::||..::..|.|.:||:|.|.:....::::||||||||:|.||:||.:|...
  Rat    69 RDENPD--FRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIA 131

  Fly   158 TKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDPPADPHKVMQACEWLTDDEVATIERKV 222
            |:.::.||..:|:|:.|.:.||||.:.:.|.:.|..|.||.||.|::.:.||:.|..|..|..|:
  Rat   132 TRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   223 LGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLIGAGKGV 287
            :|..||||.|||:|||.:|.::..:|...|:|||||...||||.|||.||.|||:||.|.||||:
  Rat   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   288 IRTMYCNSSGYGDFLPVDVAVNGILVASW-------RNITAGTDKTNRVAHMTSSNDIKVSWAEI 345
            :|||..:::...|.:||||.||..|.|:|       |||        .|.:.|:.:.....|.|:
  Rat   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNI--------MVYNCTTGSTNPFHWGEV 318

  Fly   346 IELGRWVIENKVPLNGVAWYPGGSMKSNYWVHFICMVLFQW------MPALFVDALLWILRYPPV 404
            .:......:.. |||.|..:|.....||.      ::|..|      :|||.:|..|.:....|.
  Rat   319 GDYLNHSFKTN-PLNQVFRHPYVKFYSNN------LMLHYWKGVKHTVPALLLDLALRLTGQKPW 376

  Fly   405 LCRVQNRIYKGFEVFEYYANN--VWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVL 467
            :.:...|::|.....||:.:|  |||.||..  .|...:|.::::|:.|:..:|...:|..|..:
  Rat   377 MMKTITRLHKAMVFLEYFTSNSWVWNTDNVN--MLMNQLNPEDKKTFNIDVRQLHWAEYIENYCM 439

  Fly   468 CARRLILKESDESIPAARRHMK---------------VMWVV----DKVYKGIWIFGILYMLYR 512
            ..::.:|.|....:||||:|:.               ::|.:    .::.:.||.| ::.:.|:
  Rat   440 GTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYF-VVSLCYK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1441	NP_610535.1	FAR-N_SDR_e	35..348	CDD:187547	135/319 (42%)
		Sterile	384..475	CDD:460779	24/98 (24%)
Far1	NP_001011933.1	FAR-N_SDR_e	11..330	CDD:187547	135/329 (41%)
		Sterile	371..447	CDD:460779	18/77 (23%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		10/53 (19%)