Protein Alignment CG1513 and PLEKHA8

DIOPT Version :9

• Sequence 1: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001183955.1
• Gene: PLEKHA8 / 84725
• HGNCID: 30037
• Length: 519
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 125/615 - (20%)
• Similarity: 212/615 - (34%)
• Gaps: 204/615 - (33%)

  Fly    24 LEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKGVRRGCVRLKDALIGIDDQEDNTFT 88
            :||.|.||||.:.|||.|:|:|  ..|:||||.|.:...||. :|.:::....|.:...::....
Human     1 MEGVLYKWTNYLSGWQPRWFLL--CGGILSYYDSPEDAWKGC-KGSIQMAVCEIQVHSVDNTRMD 62

  Fly    89 ITV-DHKTFHFQARHNEEREQWVRRLEDTIRRHANRSRLWDSQSAFYIAGGYTKEGGGSGTGGRR 152
            :.: ..:.|:.:||...||::|:..|...      ::.|.||::        .||       ...
Human    63 LIIPGEQYFYLKARSVAERQRWLVALGSA------KACLTDSRT--------QKE-------KEF 106

  Fly   153 PNHLELVARRVSEADAYLQLMIEQTNLLDKRIAELTDPAEQSK-----CKALQDNANAMLDHIKH 212
            ..:.|.:..::||...|..|:::|   :||.....|.....|:     ...|:...|..|..::.
Human   107 AENTENLKTKMSELRLYCDLLVQQ---VDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEE 168

  Fly   213 SIVSLQIAKNMAHPINGIYNGPPATASTSSSTSG----------------VAMGSCNNVQAGGLK 261
               .:||| |.|.....:|..||.:...:...|.                :.:.:|.|   |.|.
Human   169 ---CMQIA-NAAFTSELLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCEN---GSLN 226

  Fly   262 VPLEGQVIGKGELVDDEEDSATENATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSPIG 326
            :.:.|           ||:...:|..:..|.......|.||.|..       ||..|..|..
Human   227 MEING-----------EEEILMKNKNSLYLKSAEIDCSISSEENT-------DDNITVQGEI--- 270

  Fly   327 CATRGFAETTSPTHEKAPDGFANAEPVAVGDSVAPQTLPEIDESVADADTSIKTARTAVSSRSAS 391
                           :..||.                     |::.:.|.::        ::|.|
Human   271 ---------------RKEDGM---------------------ENLKNHDNNL--------TQSGS 291

  Fly   392 YDNGIDYDALYEEEEETDLSMEAHGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFA 456
             |:....:.|:||.:|                            |:|||.....:
Human   292 -DSSCSPECLWEEGKE----------------------------VIPTFFSTMNT---------- 317

  Fly   457 HPDLFIKISDLDDPRDRIVQVCRWYMSAYHAGRKSAVAKKPYNPILGE----VF-QCHWDIPGIS 516
                  ..||::...|..:....:..|.|      ||.     |:|.:    || ....|:.|
Human   318 ------SFSDIELLEDSGIPTEAFLASCY------AVV-----PVLDKLGPTVFAPVKMDLVG-- 363

  Fly   517 QDAQEVRDGPVPWCRRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKS--KFLGLSIGV 579
             :.::|....:  ..:::.|.|.:.|.|.  :.|..|:..|.  ...|.:|.|.  |||
Human   364 -NIKKVNQKYI--TNKEEFTTLQKIVLHE--VEADVAQVRNS--ATEALLWLKRGLKFL------ 415

  Fly   580 HNIGEGVVTLVDRSEEYIVT-FPNGYGRSI 608
                :|.:|.|...|:.|.| ..|.||:::
Human   416 ----KGFLTEVKNGEKDIQTALNNAYGKTL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	30/101 (30%)
		PH	25..118	CDD:278594	30/93 (32%)
		Oxysterol_BP	421..767	CDD:279564	40/196 (20%)
PLEKHA8	NP_001183955.1	PH_FAPP1_FAPP2	1..100	CDD:269951	33/107 (31%)
		Glycolipid transfer protein homology domain	310..519		38/178 (21%)
		GLTP	333..470	CDD:312299	33/139 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910