DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1513 and Osbpl5

DIOPT Version :9

Sequence 1:	NP_610534.3	Gene:	CG1513 / 36028	FlyBaseID:	FBgn0033463	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001015024.2	Gene:	Osbpl5 / 361686	RGDID:	1308402	Length:	898	Species:	Rattus norvegicus

Alignment Length:	497	Identity:	154/497 - (30%)
Similarity:	239/497 - (48%)	Gaps:	67/497 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 ATSYSSSEGEEDFYDAYDDPFTSIGSSPIGCATRGFAETTS---PTHEKAPDGFANAEPVAVGDS 358
            :|.....:||:             ||||....:..:...||   |..:..|...:..|..|..|.
  Rat   275 STCKQGRDGEQ-------------GSSPDASPSSLYGLPTSATIPDQDLFPLNGSALENDAFSDK 326

  Fly   359 VAPQTLPEIDESVADADTSIKTARTAVSS-----------RSASYDNGIDYD-ALYEEEEETDLS 411
            ...:   ..|:|  ||:|...:.:|..|.           |..:|...:..: ...:|..:.:..
  Rat   327 SERE---NADDS--DAETQDHSRKTNESGSDLLDSPGGPRRGTTYVEQVQEELGELDETSQVETV 386

  Fly   412 MEAHGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDLDDPRDRIVQ 476
            .|.:.|::..||.|::.||||::||||||:||.||.|...:||:.|.||..:.:..|||..||..
  Rat   387 SEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIKL 451

  Fly   477 VCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRRDQLTF-LAE 540
            |.|||:|.::  :|....||||||||||.|:|.|..|                 :.:..|| :||
  Rat   452 VLRWYLSGFY--KKPKGIKKPYNPILGETFRCCWLHP-----------------QTNSHTFYIAE 497

  Fly   541 QVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTLVDRSEEYIVTFPNGYG 605
            |||||||:||||..:.......:..:..||||.|.|:.....|:..:|.::|.|||.:|.|..:.
  Rat   498 QVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRKEEYTLTMPYAHC 562

  Fly   606 RSIL--TVPWIELGGSVEIKCPQSGYYANVEFLTKPFYGGKR--NRVSAEVYAPSEKKPFVSITG 666
            |.:|  |:. :||||.|.|:|.::...|.::|..|||:|...  |::|.::  .|.::....:||
  Rat   563 RGLLYGTMT-MELGGKVTIQCEKNNLQAELDFKLKPFFGSSTSINQISGKI--TSGEEVLARLTG 624

  Fly   667 EWSGLMEAKWHDKNKTEVF----VDVNRIPIFKKQVRPIVEQDEYESRRVWKEVTAGLKFNDIER 727
            .|...:..|......|::|    .:|.|..: |:....:.||.|.||.|:|:.||..:...|..:
  Rat   625 HWDRDVFIKEEASGGTKLFWTPSEEVRRQRL-KRHTVLLEEQSELESERLWQHVTRAIHEGDQHK 688

  Fly   728 ATTAKFVVEQQQRDQAKVRKEYDLAWEHKHF--KPVGDNWIY 767
            ||..|.|:|:.||.:|:..::....|:.:.|  .|:...|.|
  Rat   689 ATQEKSVLEEAQRQRAREHQQSLTPWKPQLFTLDPLTQEWRY 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444
		PH	25..118	CDD:278594
		Oxysterol_BP	421..767	CDD:279564	127/356 (36%)
Osbpl5	NP_001015024.2	PH_OPR5_ORP8	144..272	CDD:270103
		PH	151..267	CDD:278594
		Oxysterol_BP	397..732	CDD:279564	128/357 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D949920at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820