DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1513 and SPBC646.08c

DIOPT Version :9

Sequence 1:	NP_610534.3	Gene:	CG1513 / 36028	FlyBaseID:	FBgn0033463	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_595366.1	Gene:	SPBC646.08c / 2541093	PomBaseID:	SPBC646.08c	Length:	516	Species:	Schizosaccharomyces pombe

Alignment Length:	468	Identity:	108/468 - (23%)
Similarity:	178/468 - (38%)	Gaps:	122/468 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   402 YEEEEETDLSMEAHGSMITHLLSQVKIGM-DLT--KVVLPTFILERRSLLEMYADYFAHPDLFIK 463
            |::|       |....::..:|.|. ||: |:.  :..||..:||....|| |.:|...||.|..
pombe    33 YQKE-------EGKFKLVLSILKQC-IGVKDIASLRFSLPAQLLEPVGNLE-YWNYVDRPDYFAV 88

  Fly   464 ISDLDDPRDRIVQVCRWYMS---AYHAGRKSAVAKKPYNPILGEVFQCHWDI--PGI-------- 515
            :.|.||..:|::.|.||:.:   .:..||    ..||||.:|||.|:|.|.:  |.:
pombe    89 MGDSDDELERMLGVLRWWFTKDLRFVRGR----VVKPYNSVLGEFFRCKWVVTDPTVREDHTLDP 149

  Fly   516 --------------------------------------------------------------SQD 518
                                                                          :||
pombe   150 DSSQLPTYKTEYSETTKFPLGKSYRPKASRTTSSQSVASTMTKSSTKTSKKKSSKKNSKSESNQD 214

  Fly   519 AQEVRDGPVPWC-------------RRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKS 570
            :...|....|..             .:..:.|:|||.||||.:||||....:|.|..........
pombe   215 SSNDRSSTAPSTAESNNEHLSSSQKSKHSIVFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAV 279

  Fly   571 KFLGLSIGV--HNIGEGVVTLVDR--SEEYIVTFPNGYGRSILTVP-WIELGGSVEIKCPQSGYY 630
            .|.|.|..|  .::.:||....::  :|||:.|.|:.....||... .|.|..|..|.||::...
pombe   280 GFTGTSFKVCAGDLNKGVYVRFNKRDNEEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIK 344

  Fly   631 ANVEFLTKPFYGGKRNRVSAEVY-------------APSEKKPFVSITGEWSGLMEAKWHDKNKT 682
            ..:.::.:.:.|..|:.|....|             |..::....:..|.|...:...:..::::
pombe   345 TIITYIEERWLGKPRSLVEGVCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESES 409

  Fly   683 EVFVDVNRIPIFKKQVRPIVEQDEYESRRVWKEVTAGLKFNDIERATTAKFVVEQQQRDQAKVRK 747
            .:.||:|.:.:..|:..|:.:|..:|||::|..||..:......:||.||..:|.|||..:..|:
pombe   410 RMLVDLNELDLVHKRCPPLDKQFPFESRKIWFPVTHNILAKHYTQATKAKQEIEDQQRQASAARE 474

  Fly   748 EYDLAWEHKHFKP 760
            |....|:.:.|.|
pombe   475 ESHTEWKPRFFVP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444
		PH	25..118	CDD:278594
		Oxysterol_BP	421..767	CDD:279564	105/449 (23%)
SPBC646.08c	NP_595366.1	Oxysterol_BP	43..499	CDD:279564	105/451 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810