DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1513 and SPCC23B6.01c

DIOPT Version :9

Sequence 1:	NP_610534.3	Gene:	CG1513 / 36028	FlyBaseID:	FBgn0033463	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_588124.2	Gene:	SPCC23B6.01c / 2539266	PomBaseID:	SPCC23B6.01c	Length:	479	Species:	Schizosaccharomyces pombe

Alignment Length:	367	Identity:	126/367 - (34%)
Similarity:	199/367 - (54%)	Gaps:	20/367 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   402 YEEEEETDLSMEAHG-SMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKIS 465
            :|:::.....:|..| ::|..::||::..|||:||..|||:||.:|:||...::.:||||.:.:.
pombe     3 HEKQDRDAEEIEDEGKNIILGIVSQLRPNMDLSKVTFPTFVLEPKSMLERITNFMSHPDLLLNVQ 67

  Fly   466 DLDDPRDRIVQVCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDI-PGISQD--AQEVRDGPV 527
            ...||..|.:.|.|:|||.:|...:.  .|||.||||||.|...|.. |..|:|  .|::....|
pombe    68 KTADPEMRFLDVVRFYMSGWHIRPRG--VKKPLNPILGETFTGFWKFPPSNSKDPNLQKLHGIAV 130

  Fly   528 PWCRRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGV--VTLV 590
                     :.||||.|||||||::......|:.....|..:|:|||.|..  :|.||:  :.|.
pombe   131 ---------YAAEQVCHHPPISAYFYLCPEYKVRIDGVVKPRSRFLGNSAA--SIMEGIASIKLQ 184

  Fly   591 DRSEEYIVTFPNGYGRSILTVPW-IELGGSVEIKCPQSGYYANVEFLTKPFYGGKRNRVSAEVYA 654
            |..|||::|.||.|.|.||.... :|||..|.::||::...|::||..|.|..|..|.::.:|..
pombe   185 DLDEEYLITQPNVYARGILFGKMRLELGDHVTVRCPKTDLQADIEFKVKGFISGTYNSIAGKVKR 249

  Fly   655 PSEKKPFVSITGEWSGLMEAKWHDKNKTEVFVDVNRIPIFKKQVRPIVEQDEYESRRVWKEVTAG 719
            .|..:....|:|:|...|..:.....:|...:||::..::....||:.||.|.||:|:|.:....
pombe   250 VSTGEVLYKISGKWDSEMSVESVKTGETRPLLDVSKHDVYLVSARPLEEQGERESQRLWYKTCQA 314

  Fly   720 LKFNDIERATTAKFVVEQQQRDQAKVRKEYDLAWEHKHFKPV 761
            :...|...||..|..:|.:||::||.|:..::.|:.|:||.:
pombe   315 VIARDQTTATETKSAIEDRQREEAKQREIENVQWKPKYFKMI 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444
		PH	25..118	CDD:278594
		Oxysterol_BP	421..767	CDD:279564	122/347 (35%)
SPCC23B6.01c	NP_588124.2	Oxysterol_BP	26..354	CDD:279564	120/340 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R635
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.800