DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12744 and Zfp770

DIOPT Version :9

Sequence 1:	NP_610530.1	Gene:	CG12744 / 36024	FlyBaseID:	FBgn0033459	Length:	160	Species:	Drosophila melanogaster
Sequence 2:	NP_780675.1	Gene:	Zfp770 / 228491	MGIID:	2445100	Length:	705	Species:	Mus musculus

Alignment Length:	150	Identity:	39/150 - (26%)
Similarity:	57/150 - (38%)	Gaps:	32/150 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SCLLCEQTFDATEKLDEHLPTHFPQPVSTGQ---TCDICGRTMRSSLELHQHYKRYHEAHVPNTE 72
            :|.:|.:.|.:..|||.|...|      |||   .|.:|.::.|.|..|..|...:.|      |
Mouse   165 ACTICGKMFPSQSKLDRHSLIH------TGQRPFKCVLCSKSFRQSTHLKIHQLTHSE------E 217

  Fly    73 GHFQCQLCDKVFLLQDHLKVHVKIEHATDGYQPDEKSLDWQHYSPRSLDTTNDYKLDPILCPPPK 137
            ..|||..|.|.|.:|..|..|.:|.......|    :|..:..||.|             ||.|.
Mouse   218 RPFQCCFCQKGFKIQSKLLKHKQIHTRNKTLQ----NLPLKVKSPES-------------CPLPN 265

  Fly   138 RKYPPRSPFFNPNLWLGADN 157
            :....:..|.:.::....:|
Mouse   266 KLNAKQDAFESGDMGESEEN 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12744	NP_610530.1	C2H2 Zn finger	12..32	CDD:275368	7/19 (37%)
		C2H2 Zn finger	43..64	CDD:275368	6/20 (30%)
		C2H2 Zn finger	77..96	CDD:275368	7/18 (39%)
Zfp770	NP_780675.1	C2H2 Zn finger	33..53	CDD:275368
		zf-H2C2_2	46..70	CDD:404364
		C2H2 Zn finger	61..81	CDD:275368
		C2H2 Zn finger	87..107	CDD:275368
		C2H2 Zn finger	166..186	CDD:275368	7/19 (37%)
		zf-H2C2_2	179..203	CDD:404364	9/29 (31%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		C2H2 Zn finger	487..507	CDD:275368
		zf-H2C2_2	500..524	CDD:404364
		C2H2 Zn finger	515..535	CDD:275368
		C2H2 Zn finger	642..662	CDD:275368
		zf-H2C2_2	655..679	CDD:404364
		C2H2 Zn finger	670..690	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5639
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950