DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lime and Zfp787

DIOPT Version :9

Sequence 1:	NP_610529.1	Gene:	Lime / 36023	FlyBaseID:	FBgn0033458	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001013030.1	Gene:	Zfp787 / 67109	MGIID:	1914359	Length:	381	Species:	Mus musculus

Alignment Length:	355	Identity:	73/355 - (20%)
Similarity:	116/355 - (32%)	Gaps:	121/355 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 YSP-PLEPEIPFQMPAVHQHPIQI-----------PPMYMTAQHTAYEPPVQFLGHRPLELRQKL 225
            :|| ||:.|  .|..|.|::|:.|           ||..::...:|  ||
Mouse     8 WSPGPLDSE--DQQMASHENPVDILIMDDDDVPSWPPTKLSPPQSA--PP--------------- 53

  Fly   226 PMSPQSPLEPSGHPMASAIPSNQHTSLEMQNLCVPEGILTRVEEPPVLENPRPQAQDPIQDAGAG 290
            |..|..|..|:.:.......|..|.|.           |||.:.....|.|     :...|.|..
Mouse    54 PGPPPRPRPPAPYICTECGKSFSHWSK-----------LTRHQRTHTGERP-----NACTDCGKT 102

  Fly   291 KSRSAVLIEPKPPNAKSLAFNQGQFECNWCGKRLSSRQSLKYHE---------------SHFHGN 340
            .|:|:.|::     .:.:...:..:.|:.||||.|...:|..|:               ..|..:
Mouse   103 FSQSSHLVQ-----HRRIHTGEKPYACSECGKRFSWSSNLMQHQRIHTGEKPYTCPDCGRSFTQS 162

  Fly   341 KELAVNRLEKNLTKQHKCLTCKKRYKRRTFLLMHMKVKHGIAFPG-----------RVNADPEYP 394
            |.||.:|...:..|...|..|.:.:.:...|..|:::...::.||           |..| ||..
Mouse   163 KSLAKHRRSHSGLKPFVCPRCGRGFSQPKSLARHLRLHPELSGPGVAAKVLAASVRRAKA-PEEA 226

  Fly   395 KSVDSPVSAKVPVSP------MSSPNEAPKKEIWSTRIFNAVAAAKYQPASERADKYLVAPRQQT 453
            .:.|..::  :||..      :..|.:            .|.|||.......||
Mouse   227 TAADGEIA--IPVGDGEGIIVVGPPGD------------GAAAAAALAGVGTRA----------- 266

  Fly   454 EQLESGFTITSKRTYPLRSPYFNPDLWLDC 483
                   |.|..|..|...||    :.::|
Mouse   267 -------TGTRSRRAPAPKPY----VCMEC 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lime	NP_610529.1	C2H2 Zn finger	317..336	CDD:275368	8/33 (24%)
Lime	NP_610529.1	C2H2 Zn finger	358..377	CDD:275368	4/18 (22%)
Zfp787	NP_001013030.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..65		19/75 (25%)
		zf-C2H2	66..88	CDD:395048	6/32 (19%)
		C2H2 Zn finger	68..88	CDD:275368	6/30 (20%)
		COG5048	<93..200	CDD:227381	24/116 (21%)
		C2H2 Zn finger	96..116	CDD:275368	5/24 (21%)
		C2H2 Zn finger	124..144	CDD:275368	8/19 (42%)
		C2H2 Zn finger	152..172	CDD:275368	5/19 (26%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		C2H2 Zn finger	282..302	CDD:275368	1/4 (25%)
		C2H2 Zn finger	319..339	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100