DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lime and MEP-1

DIOPT Version :9

Sequence 1:	NP_610529.1	Gene:	Lime / 36023	FlyBaseID:	FBgn0033458	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001137875.1	Gene:	MEP-1 / 38327	FlyBaseID:	FBgn0035357	Length:	1152	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	69/362 - (19%)
Similarity:	113/362 - (31%)	Gaps:	86/362 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LARSEHINVPEGTVLCVPCYLCKQPFNDIESFK-EHLTQHAAEINAWNNTRAQEQTPPPTITPFV 126
            :|.:.|...|....:...|..|        :|: .:.|:....:.|.:|.:|:...|    .|:.
  Fly   694 MAMANHYETPHMNGVLYKCNFC--------TFEIRNATEIVYHMEAVHNIKARLIKP----LPYH 746

  Fly   127 QSMNKPFVHPTDQHLFHSIDHGDMD---HHHNAHYRNRMEFGCPPPMDFYSPPLEPEIP------ 182
            |..|..|.           |:|...   |......:.|.|....||.|:.:|...|.|.
  Fly   747 QCPNCGFE-----------DNGKAKLARHQPVCAKKFRPELNLAPPNDWEAPAKIPRIKPRHGLV 800

  Fly   183 -----------------------FQMPAVHQHPIQIPPMYMTAQHTAYEPPVQFLGHRPLELRQK 224
                                   .|..|..|....:....:.||:.|             ::||:
  Fly   801 GTATAYQAMAAQAAAQKAALANIQQQQAAAQARNNLQAAALAAQNAA-------------KMRQR 852

  Fly   225 LPMSPQSPLEPSGHPMASAIPSNQHTSLEMQNLCVPEGILTRVE------EPPVLENPRPQAQDP 283
            .|..|:..:..:..|:......|...||. .:..:..|.|.:..      :|.:...|.|:....
  Fly   853 APQPPKQNIVRNPAPVRGGNAMNAGLSLP-NSYQLAAGQLVQASKKPMAGQPSISITPLPRQSSV 916

  Fly   284 IQDAGAGKSRSAVLIEPKPPNAKSLAFNQGQFE-CNWCGKRLSSRQSLKYHESHFHGNK---ELA 344
            ...|||..|::........|.......|:.||. |..|...:...:.|:.|....|..|   ::.
  Fly   917 GAGAGASSSKAPQAAAGMKPGQSPSGNNKAQFVICEICDGYIKDLEQLRNHMQWMHKVKIHPKMI 981

  Fly   345 VNRLEKNLTKQHKCLTCKKRYKRRTFLLMHMKVKHGI 381
            .||...|      |..|:.|:.....|..|:...||:
  Fly   982 YNRPPLN------CQKCQFRFFTDQGLERHLLGSHGL 1012

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lime	NP_610529.1	C2H2 Zn finger	317..336	CDD:275368	4/18 (22%)
Lime	NP_610529.1	C2H2 Zn finger	358..377	CDD:275368	5/18 (28%)
MEP-1	NP_001137875.1	BSP_II	<121..>226	CDD:283165
		C2H2 Zn finger	951..977	CDD:275371	6/25 (24%)
		C2H2 Zn finger	989..1010	CDD:275371	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100