DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lime and hang

DIOPT Version :9

Sequence 1:	NP_610529.1	Gene:	Lime / 36023	FlyBaseID:	FBgn0033458	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001138204.1	Gene:	hang / 32613	FlyBaseID:	FBgn0026575	Length:	2223	Species:	Drosophila melanogaster

Alignment Length:	439	Identity:	89/439 - (20%)
Similarity:	145/439 - (33%)	Gaps:	137/439 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 CYLCKQPFNDIESFKEHLTQHAAEINAWNN--TRAQEQTPPP---TITPFVQS------------ 128
            |.:|...|::......|:..|....||.|.  ..|...||..   |.||...|
  Fly  1174 CPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPATDSELGVGGTMSESA 1238

  Fly   129 ----MNKPFV----HPTDQHLFHSIDHGDMDHHHNAHYRNRMEFGCPPPMDFYSPPLEPEIPFQM 185
                .|.|..    .|.:|.:|..    .:|...:..:| ||.  |......:|.  :....:.|
  Fly  1239 PATPANVPPAMANQTPQEQAVFRR----SLDQAADRRFR-RMR--CRICQRRFSS--KKSYRYHM 1294

  Fly   186 PAVHQ-HPIQIPPMYMTAQHTAYEPPVQ---FLGH-----RPLELRQ------KLPMSPQSPLEP 235
            ...|| ..:|.....:.....|||..::   |..|     ..:.::|      .:..|.:|.|:.
  Fly  1295 LTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGKAIKDEMIIKQFECDVCSIVYSSESELQQ 1359

  Fly   236 ---SGHPMASAIPSNQHTSLEMQNLCVPEGILTRVEEPPVLENPRPQAQDPIQD----AGAGKSR 293
               |.|.:.||..|...::            .:::::..::::.:|.:.| :.|    |..|.:.
  Fly  1360 HKRSVHKLTSASASTSAST------------SSKIDDDSLMDDGKPTSSD-LADLSTLAAGGSTA 1411

  Fly   294 SAVLIEPKPPNAKSLAFNQGQFECNWCGKRLSSRQSLKYHESHFHGNKELA--VNRLEKNLTKQH 356
            ||.|.               .::|.:|             .|:|:.||:||  :|..::..:..:
  Fly  1412 SAPLY---------------WYQCKYC-------------PSNFNTNKKLAIHINSHDEFDSNDY 1448

  Fly   357 KCLTCKKRYKRRTFLLMHMKVKHGIAFPGRVNADPEYPKSVDSPVSAKVPVSPMSSPNEAP---K 418
            .|..|...|..|..|.:|...||           |:.|...:..:..||........|..|   :
  Fly  1449 SCKDCGNVYSGRKSLWVHRYKKH-----------PQVPNPAECSLCRKVFFDRQMHDNHTPTCNR 1502

  Fly   419 KEIWSTRIFNAVAAAKYQPASERADKYLVAPRQQTEQLESGFTITSKRT 467
            |.|.||.                      |.:||..||.|..  |:|||
  Fly  1503 KPITSTG----------------------AHQQQDGQLHSHH--TAKRT 1527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lime	NP_610529.1	C2H2 Zn finger	317..336	CDD:275368	2/18 (11%)
Lime	NP_610529.1	C2H2 Zn finger	358..377	CDD:275368	6/18 (33%)
hang	NP_001138204.1	zf-AD	80..154	CDD:285071
		C2H2 Zn finger	1036..1057	CDD:275368
		C2H2 Zn finger	1067..1088	CDD:275368
		C2H2 Zn finger	1279..1298	CDD:275371	2/20 (10%)
		C2H2 Zn finger	1308..1325	CDD:275371	3/16 (19%)
		C2H2 Zn finger	1420..1440	CDD:275368	9/32 (28%)
		C2H2 Zn finger	1450..1468	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100