Protein Alignment Ntmt and NTMT1

DIOPT Version :10

• Sequence 1: NP_610528.1
• Gene: Ntmt / 36022
• FlyBaseID: FBgn0033457
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_054783.2
• Gene: NTMT1 / 28989
• HGNCID: 23373
• Length: 223
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 93/226 - (41%)
• Similarity: 134/226 - (59%)
• Gaps: 10/226 - (4%)

  Fly    52 STKVAAPESEFYNKAQKYWSEVPATVNGMLGGLGYISAIDIQGSNVFLREI-----RVPGNRLAL 111
            :::|...|.:||:||:.||.::|.||:|||||.|:||:|||..|..||:..     ...|...||
Human     2 TSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCAL 66

  Fly   112 DCGAGIGRVTRNLLIPRFSCVDLVEQDPAFADKAREYCTSEDGSRGKVGQIYNVGLQKFTP-TQQ 175
            ||||||||:|:.||:|.|..||:|:....|..:|:.| ..|:|.|  |...:..|||.||| ...
Human    67 DCGAGIGRITKRLLLPLFREVDMVDITEDFLVQAKTY-LGEEGKR--VRNYFCCGLQDFTPEPDS 128

  Fly   176 YDLVWTQWVLGHLTDRDLVSFFRRIKQGLAPGAFLCLKENVSSSKKTVEDRNDSSVTRPLDSYEH 240
            ||::|.|||:|||||:.|..|.||.|..|.|...:.:|:|::.....::| .||||.|.||....
Human   129 YDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKDNMAQEGVILDD-VDSSVCRDLDVVRR 192

  Fly   241 FLKEAGFRIVRKVKQQNFPKGLFPVYMIACK 271
            .:..||..::.:.:|:|.|..::.||..|.:
Human   193 IICSAGLSLLAEERQENLPDEIYHVYSFALR 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntmt	NP_610528.1	Methyltransf_PK	59..271	CDD:461771	92/217 (42%)
NTMT1	NP_054783.2	Methyltransf_PK	8..223	CDD:461771	92/218 (42%)