DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PCB and MCCA

DIOPT Version :9

Sequence 1:	NP_001163103.1	Gene:	PCB / 36020	FlyBaseID:	FBgn0027580	Length:	1197	Species:	Drosophila melanogaster
Sequence 2:	NP_849583.1	Gene:	MCCA / 838362	AraportID:	AT1G03090	Length:	734	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	212/482 - (43%)
Similarity:	291/482 - (60%)	Gaps:	23/482 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 VRLNAIFKNGYSSKVEY-------KP----IRSVLVANRGEIAIRVFRACTELGIKSVAVYSEQD 73
            :|.|...|| :|..|.|       ||    |..:|||||||||.|:.|....|||::|||||:.|
plant     9 LRRNVRRKN-HSMLVRYISGSASMKPKEQCIEKILVANRGEIACRIMRTAKRLGIQTVAVYSDAD 72

  Fly    74 KMHMHRQKADESYIVGKGLPPVE--AYLNIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDA 136
            :..:|.:.|||:..:|   ||..  :||:...::.........|:|||||||||.|||||...|:
plant    73 RDSLHVKSADEAVRIG---PPSARLSYLSGVTIMEAAARTGAQAIHPGYGFLSESSDFAQLCEDS 134

  Fly   137 GLRFIGPSPEVVQKMGDKVAARVAAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGG 201
            ||.||||....::.||||.|::.....||||:|||..|.....:......:|.|.|:|.|..:||
plant   135 GLTFIGPPASAIRDMGDKSASKRIMGAAGVPLVPGYHGHEQDIDHMKSEAEKIGYPIIIKPTHGG 199

  Fly   202 GGRGMRVVRKMEDVEESFQRASSEAKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERD 266
            ||:|||:|:..:|..:||..|..||.|:||...:.:||:|.||||||||:.|||.|||:||||||
plant   200 GGKGMRIVQSGKDFADSFLGAQREAAASFGVNTILLEKYITRPRHIEVQIFGDKHGNVLHLYERD 264

  Fly   267 CSVQRRHQKVVEIAPAPRLPIEIRDKMTEAAVRLARHVGYENAGTVEFLCD-ESGNFYFIEVNAR 330
            |||||||||::|.||||.:..:.|..:.:|||..||.|||.|||||||:.| ||..|||:|:|.|
plant   265 CSVQRRHQKIIEEAPAPNISEKFRANLGQAAVSAARAVGYYNAGTVEFIVDTESDQFYFMEMNTR 329

  Fly   331 LQVEHTVTEEITGIDLVQSQIRVAEGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDFQPNTGR 395
            |||||.|||.|.|.|||:.|||||.|..||   .:|.::...|:|.:.|:..|:....|.|.||.
plant   330 LQVEHPVTEMIVGQDLVEWQIRVANGEPLP---LSQSEVPMSGHAFEARIYAENVPKGFLPATGV 391

  Fly   396 LEVFRS-GEGMGIRLDSASAYAGAIISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKT 459
            |..:|. .....:|::: ....|..:|.:||.::.|::....:...:..|:...|..|::.||.|
plant   392 LNHYRPVAVSPSVRVET-GVEQGDTVSMHYDPMIAKLVVWGGNRGEALVKLKDCLSNFQVAGVPT 455

  Fly   460 NIPFLLNVLENQKFLHGVLDTYFIDEH 486
            ||.||..:..:::|..|.::|:||:.|
plant   456 NINFLQKLASHKEFAVGNVETHFIEHH 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PCB	NP_001163103.1	CPSase_L_chain	39..147	CDD:278706	52/109 (48%)
		pyruv_carbox	41..1197	CDD:130302	202/450 (45%)
		ATP-grasp_4	153..360	CDD:302634	114/207 (55%)
		Biotin_carb_C	377..484	CDD:214878	28/107 (26%)
		DRE_TIM_PC_TC_5S	584..867	CDD:163675
		PYC_OADA	880..1078	CDD:280576
		biotinyl_domain	1130..1196	CDD:133459
MCCA	NP_849583.1	PccA	38..734	CDD:227111	203/452 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D254436at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920