Protein Alignment PCB and mccc-1

DIOPT Version :10

• Sequence 1: NP_724841.1
• Gene: PCB / 36020
• FlyBaseID: FBgn0027580
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_501777.2
• Gene: mccc-1 / 177841
• WormBaseID: WBGene00009319
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 763
• Identity: 260/763 - (34%)
• Similarity: 379/763 - (49%)
• Gaps: 136/763 - (17%)

  Fly    37 KPIRSVLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPV--EAYL 99
            :||:.|||||||||||||.....::||::|||:|:.|:..:..:|||::|.:|   ||:  |:||
 Worm    17 RPIQRVLVANRGEIAIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIG---PPLAAESYL 78

  Fly   100 NIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARVAAIEA 164
            |:.::|.....:...|:|||||||||.:.||:....|||.||||..:.::.||.|..::....:|
 Worm    79 NMDKIINSALRSGAQAIHPGYGFLSENAGFAEKCAQAGLVFIGPPAQAIRDMGAKNVSKQIMEDA 143

  Fly   165 GVPIVPGTDG----PVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSE 225
            .||:|.|..|    ....|:::.|.    |.||:.||.|||||:|||:.....:.||....|.:|
 Worm   144 KVPVVKGFHGEDQSDANLKKKSAEI----GYPVMLKAVYGGGGKGMRIAWNEAEFEEKLASARNE 204

  Fly   226 AKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEIAPAPRLPIEIR 290
            ||.:|||..|.:|||:|:|||:|||:.||..||.|||:||||||||||||::|.||||.:..:.|
 Worm   205 AKKSFGNDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDCSVQRRHQKIIEEAPAPNMEHDTR 269

  Fly   291 DKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIRVAE 355
            .|:.|:|||.|..|||..||||||:.|..|.|||:|:|.||||||.|:|.|||.|||:.|:|||:
 Worm   270 VKLGESAVRAAAAVGYVGAGTVEFIMDPRGEFYFMEMNTRLQVEHPVSEAITGTDLVEWQLRVAQ 334

  Fly   356 GMTLPELGYTQDKIVPRGYAIQCRVTTEDPAND-FQPNTGRLEVFRSGEGMGIRLDSASAYAGAI 419
            |..||   ..|.:|...|:|.:|||..||.... |.|..|||......|  ..|:|: ...:|..
 Worm   335 GEKLP---LKQSEIPLNGHAFECRVYAEDTRKGAFMPTAGRLNYVDFPE--DARIDT-GVVSGDE 393

  Fly   420 ISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKTNIPFLLNVLENQKFLHGVLDTYFID 484
            :|.:||.::.||:....|...:|:|:..||...||.|:.|||.|:..||.:.:|..|.:.|.||.
 Worm   394 VSIHYDPMIAKVVVWGQDRAVAAAKLESALARTRISGLPTNIDFVRRVLAHPEFAAGNVYTDFIP 458

  Fly   485 EHPQLFKFKPSLNRAQKLLNYMGEVLVNGPQTPLATTLKPALVSPHVPEVPLDLSPEAIEREERG 549
            :|             ||.|....|       ||....::.|:.             .|:...::.
 Worm   459 DH-------------QKELFAESE-------TPAEIYVESAVA-------------HALAALQKS 490

  Fly   550 EAKVTE---------PPKGLREVLVCEGPEAFAKEVRNRKELLLMDTTFRDAHQSLLATRVRSHD 605
            :|.|.:         .||.:.::   :|                .|.:.|....|.|.
 Worm   491 DAGVFQNLSFFRMNLSPKYIFKI---DG----------------KDVSIRFDSDSRLT------- 529

  Fly   606 LLKISPYVTHKFNNLYSLENWGGATFDVALRFLHECPWERLEEMRKRIPNIPFQMLLRGANAVGY 670
                   |::..|:..:|.|...:|.|.:.:|..|....|...:.|.:.|    .|:  .|.||.
 Worm   530 -------VSYDGNSYETLLNDIESTTDGSFKFTLEANGRRWSTVVKNLGN----SLM--VNGVGQ 581

  Fly   671 TSYPDNVVYKFCELAVQTGMDIFRVFDSLNYLPNLILGMEAAGKA----GGVVEAAISYTGDVSD 731
            ..|....:::              .||||:       |..|:..|    .|::|..:...|:...
 Worm   582 NEYETPQIHE--------------TFDSLS-------GGAASHSAVAPMPGIIEKILVKPGEQVT 625

  Fly   732 PKR-----TKYDLKYYTNLADELVKAGTHVLCIKDMAGLLKPESARLL 774
            ..:     |...::|.....::  ....|:.|   .||...|::|.|:
 Worm   626 TGQALVVMTAMKMEYIIRAPED--STVEHIKC---QAGKNVPKNAVLV 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCB	NP_724841.1	PycA	37..1196	CDD:440660	260/763 (34%)
mccc-1	NP_501777.2	PccA	18..483	CDD:443802	215/510 (42%)
		PRK05641	527..669	CDD:235540	36/188 (19%)
		biotinyl_domain	606..670	CDD:133459	12/68 (18%)