Protein Alignment PCB and Mccc1

DIOPT Version :10

• Sequence 1: NP_724841.1
• Gene: PCB / 36020
• FlyBaseID: FBgn0027580
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_319416.5
• Gene: Mccc1 / 1279652
• VectorBaseID: AGAMI1_007776
• Length: 698
• Species: Anopheles gambiae
• Alignment Length: 757
• Identity: 253/757 - (33%)
• Similarity: 369/757 - (48%)
• Gaps: 129/757 - (17%)

  Fly    31 SSKVEYKPIRSVLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPV 95
            |.||.::.|..:|:|||||||.||.|....|||::|||:|:.|:..:|.:.|:|:|.:|.....
Mosquito    23 SQKVVHRQINKLLIANRGEIACRVMRTANRLGIRTVAVFSDADEKSLHVKLANEAYNIGPAASQ- 86

  Fly    96 EAYLNIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARVA 160
            ::||...:::.|.|:....|:|||||||||..:||:......:.||||....::.||.|..::..
Mosquito    87 QSYLRGDKILAVAKKAGCQAIHPGYGFLSENVEFAELCQQEQVTFIGPPASAIRDMGIKSTSKHI 151

  Fly   161 AIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSE 225
            ...|||||:.|..|...:.|:.::..||.|.|::.||..||||:|||:.....|.....|.|.:|
Mosquito   152 MSAAGVPIINGYHGEDQSDEKLMQEAKKIGFPLMIKAVRGGGGKGMRIAETEADFMPMLQSARTE 216

  Fly   226 AKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEIAPAPRLPIEIR 290
            ::.|||:.||.:|:::..|||:|||:..|..||.|:||||||||||||||::|.||||.|..|:|
Mosquito   217 SEKAFGDSAMLLERYVRSPRHVEVQVFADHYGNAVYLYERDCSVQRRHQKIIEEAPAPGLSEELR 281

  Fly   291 DKMTEAAVRLARHVGYENAGTVEFLCD-ESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIRVA 354
            .::.|||||.|:.|.|..||||||:.| |..:|:|:|:|.||||||.:||.|||.|||:.||:||
Mosquito   282 KQLGEAAVRAAKAVNYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIKVA 346

  Fly   355 EGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDFQPNTGRLEVFRSGEGMGIRLDSASAYAGAI 419
            .|..||   .||:.||.||:|.:.|:..||||..|.|..|.|:...:.|.............|..
Mosquito   347 AGERLP---VTQEDIVKRGHAFEARIYAEDPAGGFLPGAGPLDYLSTPETSNTTRVETGVRQGDE 408

  Fly   420 ISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKTNIPFLLNVLENQKFLHGVLDTYFID 484
            :|.:||.::.|::....:..||...:...|..::|.|::|||.||:::..::.|....:.|.||:
Mosquito   409 VSIHYDPMIAKLVVWGENRASSLQLLIEQLTNYQIAGLQTNINFLIDLARHEHFQAADVHTGFIE 473

  Fly   485 EHPQLFKFKPSLNRAQKLLNYMGEVLVNGPQTPLATTLKPALVSPHVPEVPLDLSPEAIEREERG 549
            :|                                ..||.|..|.|....|.:.|:....||.:.|
Mosquito   474 QH--------------------------------TATLFPKKVIPATKVVQMALAHTLNERVQSG 506

  Fly   550 E---AKVTEP---PKGLREVLVCEGPEAFAKEVRNRKELLLMDTTFRDAHQSLLATRVRSHDLLK 608
            .   ||...|   ..|.|...  ..|.:...:|...:.::.::|. .|...|:   ||...:.:|
Mosquito   507 ASLGAKTCGPFDVEYGFRPNY--RVPRSIKIKVGAMEHIVTIETD-NDGSYSV---RVDDGEWMK 565

  Fly   609 IS----PYVTHKFNNLYSLENWGGATFDVALRFLHECPWERLEEMRKRIPNIPFQMLLRGANAVG 669
            ::    ||                     |.|||.|                        .|..|
Mosquito   566 VTVRRKPY---------------------ANRFLLE------------------------TNIEG 585

  Fly   670 YTSYPDNVVYKFCELAVQTGMDIFRVFDSLNYLPNLILGME-------AAGKAGGVVEAAISYTG 727
            :.|         |..||.:|.:| .:||.     |.::|.|       ...::.|.|:|:
Mosquito   586 HVS---------CFNAVISGENI-SLFDE-----NGMIGGEIVQPRFLVTERSMGGVDAS----- 630

  Fly   728 DVSDPKRTKYDLKYYTNLADELVKAGT--HVLCIKDMAGLLK 767
            .|:.|.....| |.:....| .|||||  .||....|..:||
Mosquito   631 SVTAPMPGVLD-KLFVKPGD-TVKAGTPVAVLIAMKMEHVLK 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCB	NP_724841.1	PycA	37..1196	CDD:440660	250/751 (33%)
Mccc1	XP_319416.5	None