Protein Alignment PCB and Pcca

DIOPT Version :9

• Sequence 1: NP_001163103.1
• Gene: PCB / 36020
• FlyBaseID: FBgn0027580
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_659093.2
• Gene: Pcca / 110821
• MGIID: 97499
• Length: 724
• Species: Mus musculus
• Alignment Length: 559
• Identity: 233/559 - (41%)
• Similarity: 329/559 - (58%)
• Gaps: 31/559 - (5%)

  Fly    32 SKVEYKP----IRSVLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGL 92
            |.|||:|    ...:|:|||||||.||.:.|.::|||:||::|:.|...:|.:.|||:..||..
Mouse    48 SSVEYEPKEKTFDKILIANRGEIACRVIKTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPA- 111

  Fly    93 PPVEAYLNIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAA 157
            |..::|||:..::...|:....|||||||||||..:||:.:....:.||||....:|.||||:.:
Mouse   112 PTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFAKRLAAEDVTFIGPDTHAIQAMGDKIES 176

  Fly   158 RVAAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRA 222
            ::.|..|.|..:||.||.|...:||:...::.|.||:.||:.||||:|||:....|:..:.|:.:
Mouse   177 KLLAKRAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRFS 241

  Fly   223 SSEAKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEIAPAPRLPI 287
            |.||.::||:..:.|||||:.|||||:|:||||.||.:.|.||:||:|||:|||||.||:..|..
Mouse   242 SQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDP 306

  Fly   288 EIRDKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIR 352
            |.|..|.|.||.||:.|.|.:|||||||.|...||||:|:|.||||||.|||.|||:||||..|.
Mouse   307 ETRQAMGEQAVALAKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIL 371

  Fly   353 VAEGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDF-QPNTGRLEVFRSGEGM-GIRLDSASAY 415
            ||:|.   .|.:.|:.|...|:|::|||..|||...| .|:.|||..::....: |:|:|| ...
Mouse   372 VAKGY---PLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDS-GIQ 432

  Fly   416 AGAIISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKTNIPFLLNVLENQKFLHGVLDT 480
            .|:.||.|||.::.|::::.||...:..:|..||..:.||||..|||.|..|:.|.:|:.|.:.|
Mouse   433 PGSDISIYYDPMISKLVTYGSDRAEALKRMEDALDNYVIRGVTHNIPLLREVIINTRFVKGDIST 497

  Fly   481 YFI-DEHPQLFK-FKPSLNRAQKLLNYMGEVLVNGPQTPLATTLKPALVSPH--VPEVPLDLSPE 541
            .|: |.:|..|| ...:|:...:||.....|.|       |:.|:......|  ||.:..|::
Mouse   498 KFLSDVYPDGFKGHTLTLSERNQLLAIASSVFV-------ASQLRAQRFQEHSRVPVIRPDVA-- 553

  Fly   542 AIEREERGEAKVTEPPKGLREVLVCEGPEAFAKEVRNRK 580
                  :.|..|....:....|....|| ||..||...|
Mouse   554 ------KWELSVKLHDEDHTVVASNNGP-AFTVEVDGSK 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCB	NP_001163103.1	CPSase_L_chain	39..147	CDD:278706	46/107 (43%)
		pyruv_carbox	41..1197	CDD:130302	228/546 (42%)
		ATP-grasp_4	153..360	CDD:302634	108/206 (52%)
		Biotin_carb_C	377..484	CDD:214878	41/109 (38%)
		DRE_TIM_PC_TC_5S	584..867	CDD:163675
		PYC_OADA	880..1078	CDD:280576
		biotinyl_domain	1130..1196	CDD:133459
Pcca	NP_659093.2	PccA	59..724	CDD:227111	228/548 (42%)
		CPSase_L_chain	59..167	CDD:278706	46/108 (43%)
		CPSase_L_D2	172..379	CDD:280881	108/209 (52%)
		Biotin_carb_C	393..500	CDD:214878	40/107 (37%)
		biotinyl_domain	657..723	CDD:133459

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D130620at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920