DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1671 and SWD3

DIOPT Version :9

Sequence 1:	NP_610526.1	Gene:	CG1671 / 36019	FlyBaseID:	FBgn0033454	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_009734.1	Gene:	SWD3 / 852472	SGDID:	S000000379	Length:	315	Species:	Saccharomyces cerevisiae

Alignment Length:	334	Identity:	71/334 - (21%)
Similarity:	128/334 - (38%)	Gaps:	86/334 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 CSELK---QLALVTTEQNILVYDVETLEPIKHLV-GYNDEILDMCFMGEHDRYLAVATNSKHFKL 364
            |:::.   |...:|...|||:||:......:.|| .:.....::|:..:..   .:||.|..|.:
Yeast    18 CAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQ---CIATASDDFSV 79

  Fly   365 ------YDTEHDMNCKLIVGHSDTVMSLAASQ--NLLISVGKDCSVRLWRLQHDKDCSLEALTQQ 421
                  |...|     ..:||:..|:||..::  |||.:...|.|:::|      |....:|.:.
Yeast    80 EIIHLSYGLLH-----TFIGHTAPVISLTFNRKGNLLFTSSMDESIKIW------DTLNGSLMKT 133

  Fly   422 ANCHTSTIGCVAMTHNGATGFASVSQDGSMKVWQLVRSKEDRNSYSFNLRYAALSHDKEVNCVAY 486
            .:.|:..:..|.:..|.::..:|.|.||.::::.
Yeast   134 ISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFD------------------------------- 167

  Fly   487 APNNKLIATASQDKTAKVWLAESNTLQGVLRGHTRGVWSVRFSPVDQIVLTSSSDCTLRIWSISN 551
            |.....:.|.:.||.   |..|:..:.         :..|:||...:.:|..|.|..::||....
Yeast   168 AETGHCLKTLTYDKD---WKRENGVVP---------ISQVKFSENARYLLVKSLDGVVKIWDCIG 220

  Fly   552 FSCIKRFDQ----ECTILR----AEFL--DHGK--FIISAASDGLLKLWNIKTNTCLQSLD---- 600
             .|:.|..|    |..:|.    .:||  :.|.  .:||...:|.:..||..|.:.||.||
Yeast   221 -GCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLY 284

  Fly   601 EHNDRVWAL 609
            .|:..|.::
Yeast   285 HHSSPVMSI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1671	NP_610526.1	WD40 repeat	22..54	CDD:293791
		WD40	64..571	CDD:225201	58/288 (20%)
		WD40 repeat	82..115	CDD:293791
		WD40	118..455	CDD:238121	37/162 (23%)
		WD40 repeat	122..159	CDD:293791
		WD40 repeat	167..206	CDD:293791
		WD40 repeat	209..236	CDD:293791
		WD40 repeat	299..335	CDD:293791	10/34 (29%)
		WD40	329..631	CDD:238121	63/306 (21%)
		WD40 repeat	340..377	CDD:293791	7/42 (17%)
		WD40 repeat	430..476	CDD:293791	6/45 (13%)
		WD40 repeat	481..517	CDD:293791	6/35 (17%)
		WD40 repeat	524..559	CDD:293791	10/34 (29%)
		WD40 repeat	564..600	CDD:293791	12/43 (28%)
		WD40 repeat	608..657	CDD:293791	0/2 (0%)
		Utp13	653..787	CDD:285789
SWD3	NP_009734.1	WD40	17..314	CDD:238121	71/334 (21%)
		WD40 repeat	17..53	CDD:293791	10/34 (29%)
		WD40 repeat	59..94	CDD:293791	7/42 (17%)
		WD40 repeat	99..135	CDD:293791	11/41 (27%)
		WD40 repeat	142..178	CDD:293791	8/66 (12%)
		WD40 repeat	192..228	CDD:293791	10/36 (28%)
		WD40 repeat	236..284	CDD:293791	14/47 (30%)
		WD40 repeat	290..312	CDD:293791	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1422
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030