DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha7 and psmb13a

DIOPT Version :9

Sequence 1:	NP_724834.1	Gene:	Prosalpha7 / 36018	FlyBaseID:	FBgn0023175	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_571752.2	Gene:	psmb13a / 64280	ZFINID:	ZDB-GENE-001208-2	Length:	281	Species:	Danio rerio

Alignment Length:	179	Identity:	45/179 - (25%)
Similarity:	69/179 - (38%)	Gaps:	29/179 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KAVEKSGTVIGIRGKDAVVLAVEKIITS-KLYEPDAGGRIFTIEKNIGMAVAGLVADGNFVADI- 91
            ||::...|:.|:..||.|||..:...|| ::.......:|..|..||....||..||.....|:
Zfish    39 KALKTGTTIAGVVFKDGVVLGADTRATSDEVVADKMCAKIHYIAPNIYCCGAGTAADTEKTTDML 103

  Fly    92 -------ARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVRPFGLSIILASWDEVEGPQL 149
                   :.....|.|......| ::.:..|..|.:            |.::||...| ..|..|
Zfish   104 SSNLTIFSMNSGRNPRVVMAVNI-IQDMLFRYHGMI------------GANLILGGVD-CTGSHL 154

  Fly   150 YKIEPSGS--SFGYFACASGKAKQLAKTEMEKLKMDMRTDE---LVESA 193
            |.:.|.||  ...|.|..||....:...| ::.|::|..::   ||..|
Zfish   155 YTVGPYGSMDKVPYLAMGSGDLAAMGILE-DRFKVNMDLEQAKALVSDA 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	45/179 (25%)
Prosalpha7	NP_724834.1	PRE1	6..231	CDD:223711	45/179 (25%)
psmb13a	NP_571752.2	proteasome_beta_type_7	45..233	CDD:239732	43/173 (25%)
psmb13a	NP_571752.2	Pr_beta_C	241..272	CDD:315191
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900