Protein Alignment Prosalpha7 and PSMB3

DIOPT Version :10

• Sequence 1: NP_724834.1
• Gene: Prosalpha7 / 36018
• FlyBaseID: FBgn0023175
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_002786.2
• Gene: PSMB3 / 5691
• HGNCID: 9540
• Length: 205
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 50/238 - (21%)
• Similarity: 93/238 - (39%)
• Gaps: 78/238 - (32%)

  Fly    35 GTVIGIRGKDAVVLAVEKI--ITSKLYEPDAGGRIFTIEKNIGMAVAGLVADGNFVADIARQEAA 97
            |.|:.::||:.|.:|.::.  |.:::...|. .:||.:...:.:.:|||..|...||.
Human     9 GAVMAMKGKNCVAIAADRRFGIQAQMVTTDF-QKIFPMGDRLYIGLAGLATDVQTVAQ------- 65

  Fly    98 NYRQQFEQAIPLKHLCHRVAGYVHAYTLYSA--VRPFGLSIILAS--WDEVEGPQLYKIEP---- 154
              |.:|.               ::.|.|...  ::|:.|..::|:  :::..||  |..||
Human    66 --RLKFR---------------LNLYELKEGRQIKPYTLMSMVANLLYEKRFGP--YYTEPVIAG 111

  Fly   155 -SGSSFGYFACASGKAKQLAKTEMEKLKMDMRTDELVES--AGEIIYKVHDEL----KDKDFRFE 212
             ...:|..|.|:           ::.:...|.||:.|.|  ..|.:|.:.:.|    .|.|..||
Human   112 LDPKTFKPFICS-----------LDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFE 165

  Fly   213 -----------------MGLVGRVTGGLHLINPSELTEKARKA 238
                             ||::      :|:|...::|.:..||
Human   166 TISQAMLNAVDRDAVSGMGVI------VHIIEKDKITTRTLKA 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	45/214 (21%)
PSMB3	NP_002786.2	proteasome_beta_type_3	6..201	CDD:239728	48/235 (20%)