Protein Alignment Prosalpha7 and PSMB1

DIOPT Version :10

• Sequence 1: NP_724834.1
• Gene: Prosalpha7 / 36018
• FlyBaseID: FBgn0023175
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_002784.1
• Gene: PSMB1 / 5689
• HGNCID: 9537
• Length: 241
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 41/223 - (18%)
• Similarity: 82/223 - (36%)
• Gaps: 45/223 - (20%)

  Fly    11 SASQFSPDGR-----------VFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITS--KLYEPD 62
            |.:.:|..||           ..|:.: |..|...||::.|.|:|..::|.:..::.  .::..|
Human     4 STAMYSAPGRDLGMEPHRAAGPLQLRF-SPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRD 67

  Fly    63 AGGRIFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYS 127
            : .:.:.:.....:..:|...|...:..|.......|:....:|:....:...::..:::...:
Human    68 S-PKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFF- 130

  Fly   128 AVRPFGLSIILASWDEVEGPQLYKIEPSGS----SFGYFACASGKA--------------KQLAK 174
               |:.:..|:...||.....:|..:|.||    ||.    |.|.|              |.:..
Human   131 ---PYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFK----AGGSASAMLQPLLDNQVGFKNMQN 188

  Fly   175 TEMEKLKMD--MR--TDELVESAGEIIY 198
            .|...|.:|  ||  .|..:.:|...:|
Human   189 VEHVPLSLDRAMRLVKDVFISAAERDVY 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	41/223 (18%)
PSMB1	NP_002784.1	proteasome_beta_type_1	30..241	CDD:239726	36/197 (18%)