Protein Alignment Prosalpha7 and PSMA4

DIOPT Version :10

• Sequence 1: NP_724834.1
• Gene: Prosalpha7 / 36018
• FlyBaseID: FBgn0023175
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_002780.1
• Gene: PSMA4 / 5685
• HGNCID: 9533
• Length: 261
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 73/252 - (28%)
• Similarity: 127/252 - (50%)
• Gaps: 11/252 - (4%)

  Fly     8 YDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLY-EPDAGGRIFTIE 71
            ||...:.|||:||::|::||.:|:..:||.:||...|.|:||.|:....||. |.....:|:.:.
Human     5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLN 69

  Fly    72 KNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVRPFGLSI 136
            :::..:|||:.:|.|.:.:..|..|..|..|:::.||.:.|...:.....|||.:...||||:|:
Human    70 EDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 134

  Fly   137 ILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEMEKLKMDMRTDEL-----VESAGEI 196
            :...||:..|.|||:.:|||:..|:.|...|.....|   :..||.|.:..|:     :..|.::
Human   135 LYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAA---VSMLKQDYKEGEMTLKSALALAIKV 196

  Fly   197 IYKVHDELKDKDFRFEMGLVGRVTGG--LHLINPSELTEKARKAGDAANKDEDSDNE 251
            :.|..|..|....:.|:..:.|..|.  :.::...|:.:..:|..:...|.|....|
Human   197 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	66/213 (31%)
PSMA4	NP_002780.1	proteasome_alpha_type_4	3..216	CDD:239721	66/213 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..261		3/14 (21%)