Protein Alignment Prosalpha7 and PSMA2

DIOPT Version :10

• Sequence 1: NP_724834.1
• Gene: Prosalpha7 / 36018
• FlyBaseID: FBgn0023175
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_002778.1
• Gene: PSMA2 / 5683
• HGNCID: 9531
• Length: 234
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 73/228 - (32%)
• Similarity: 119/228 - (52%)
• Gaps: 5/228 - (2%)

  Fly     7 GYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGGRIFTIE 71
            ||..|.:.|||.|::.||:||..||......:||:..:.||||.||...|.||:..:..::..|.
Human     5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPIT 69

  Fly    72 KNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVRPFGLSI 136
            |:||:..:|:..|...:...||:.|..|...:::.||...|..|||..:..||....|||||:|:
Human    70 KHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSL 134

  Fly   137 ILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEMEK-LKMDMRTDELVESAGEIIYKV 200
            ::..|:|.. |.|::.:|||:.|.:.|.|.||.....||.:|| ...|:..::.:.:| .:..|.
Human   135 LICGWNEGR-PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTA-ILTLKE 197

  Fly   201 HDELKDKDFRFEMGLVGRVTGGLHLINPSELTE 233
            ..|.:..:...|:|:...  .|...:.|:|:.:
Human   198 SFEGQMTEDNIEVGICNE--AGFRRLTPTEVKD 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	70/209 (33%)
PSMA2	NP_002778.1	proteasome_alpha_type_2	6..231	CDD:239719	72/227 (32%)