DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha7 and psma3

DIOPT Version :9

Sequence 1:	NP_724834.1	Gene:	Prosalpha7 / 36018	FlyBaseID:	FBgn0023175	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001011257.1	Gene:	psma3 / 496707	XenbaseID:	XB-GENE-976787	Length:	255	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	148/253 - (58%)
Similarity:	194/253 - (76%)	Gaps:	2/253 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTIGTGYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGG 65
            ||:||||||||||.|||||||||::||:||||.|.|.||||.||.||..|||::.|||||..:..
Frog     1 MSSIGTGYDLSASTFSPDGRVFQVEYAAKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65

  Fly    66 RIFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVR 130
            |||.:::::|||||||:||...:|||||:||:|:|..:...||||||..|||.||||||||||||
Frog    66 RIFNVDRHVGMAVAGLLADARSLADIAREEASNFRANYGYDIPLKHLSDRVAMYVHAYTLYSAVR 130

  Fly   131 PFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEMEKLKM-DMRTDELVESAG 194
            |||.|.:|.|::|.:|.|||.::|||.|:||:.||.|||||.||||:|||:| ||...::|:...
Frog   131 PFGCSFMLGSYNEDDGAQLYMVDPSGISYGYWGCAIGKAKQAAKTEIEKLQMKDMTCRDVVKEVA 195

  Fly   195 EIIYKVHDELKDKDFRFEMGLVGRVTGGLHLINPSELTEKARK-AGDAANKDEDSDNE 251
            :|||.||||:|||.|..|:..||::|.|.|.|.|.::.|:|.| |.::..:::|||::
Frog   196 KIIYIVHDEVKDKSFELELSWVGKITNGKHEIVPKDIREEAEKYAKESLEEEDDSDDD 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	131/211 (62%)
Prosalpha7	NP_724834.1	PRE1	6..231	CDD:223711	137/225 (61%)
psma3	NP_001011257.1	proteasome_alpha_type_3	5..217	CDD:239720	131/211 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2613
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2082
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2860
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0004628
OrthoInspector	1	1.000	-	-		oto104290
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3238
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160