DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha7 and Psma3

DIOPT Version :9

Sequence 1:	NP_724834.1	Gene:	Prosalpha7 / 36018	FlyBaseID:	FBgn0023175	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_035314.3	Gene:	Psma3 / 19167	MGIID:	104883	Length:	255	Species:	Mus musculus

Alignment Length:	252	Identity:	145/252 - (57%)
Similarity:	186/252 - (73%)	Gaps:	1/252 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTIGTGYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGG 65
            ||:||||||||||.|||||||||::||.||||.|.|.||||.||.||..|||::.|||||..:..
Mouse     1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65

  Fly    66 RIFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVR 130
            |:|.:::::|||||||:||...:|||||:||:|:|..|...||||||..|||.||||||||||||
Mouse    66 RLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVR 130

  Fly   131 PFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEMEKLKM-DMRTDELVESAG 194
            |||.|.:|.|:...:|.|||.|:|||.|:||:.||.|||:|.||||:|||:| :|...::|:...
Mouse   131 PFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVA 195

  Fly   195 EIIYKVHDELKDKDFRFEMGLVGRVTGGLHLINPSELTEKARKAGDAANKDEDSDNE 251
            :|||.||||:|||.|..|:..||.:|.|.|.|.|.::.|:|.|....:.|:||..::
Mouse   196 KIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLKEEDESDD 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	129/211 (61%)
Prosalpha7	NP_724834.1	PRE1	6..231	CDD:223711	135/225 (60%)
Psma3	NP_035314.3	proteasome_alpha_type_3	5..217	CDD:239720	129/211 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837065
Domainoid	1	1.000	213	1.000	Domainoid score	I2752
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2082
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2809
Isobase	1	0.950	-	0	Normalized mean entropy	S453
OMA	1	1.010	-	-		QHG53517
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0004628
OrthoInspector	1	1.000	-	-		oto94077
orthoMCL	1	0.900	-	-		OOG6_102011
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1005
SonicParanoid	1	1.000	-	-		X3238
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750