DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha7 and PSMB11

DIOPT Version :9

Sequence 1:	NP_724834.1	Gene:	Prosalpha7 / 36018	FlyBaseID:	FBgn0023175	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001093250.1	Gene:	PSMB11 / 122706	HGNCID:	31963	Length:	300	Species:	Homo sapiens

Alignment Length:	162	Identity:	31/162 - (19%)
Similarity:	65/162 - (40%)	Gaps:	21/162 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 TVIGIRGKDAVVLAVEKIITSKLYEP-DAGGRIFTIEKNIGMAVAGLVADGNFVADIARQEAANY 99
            |.:..|.:..|:.|.:...:...|.. .|..::..:.:::....:|..||           .|.:
Human    51 TTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSAD-----------CATW 104

  Fly   100 RQQFEQAIPLKHLCH-RVAGYVHAYTLYSAV--RPFGLSIILAS----WDEVEGPQLYKIEPSGS 157
            .:..::.:.|:.|.. ::.....|..|.||:  :..||.:.:|:    ||. .||:|:.:...|:
Human   105 YRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDR-SGPELFYVYSDGT 168

  Fly   158 SFGYFACASGKAKQLAKTEMEK-LKMDMRTDE 188
            .......:.|.....|...::: .:.||.|.|
Human   169 RLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha7	NP_724834.1	proteasome_alpha_type_3	5..216	CDD:239720	31/162 (19%)
Prosalpha7	NP_724834.1	PRE1	6..231	CDD:223711	31/162 (19%)
PSMB11	NP_001093250.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		proteasome_beta_type_5	50..237	CDD:239730	31/162 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..300
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900