Protein Alignment Orc6 and ORC6

DIOPT Version :9

• Sequence 1: NP_477319.1
• Gene: Orc6 / 36017
• FlyBaseID: FBgn0023180
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_055136.1
• Gene: ORC6 / 23594
• HGNCID: 17151
• Length: 252
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 70/250 - (28%)
• Similarity: 121/250 - (48%)
• Gaps: 18/250 - (7%)

  Fly     4 LIEQLITKMGLREEPNVLEKTTELVRLLELRSTNVPLQINEYGKIVLCADLASCMIGIAFDKEQA 68
            ||.:|..::|| .||::|.|..|.:||..::...:..:..|....|:|.|||:..:....|:...
Human     5 LIGRLAPRLGL-AEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYL 68

  Fly    69 LKLSGLRKSQYLNNKRMFEKLLDLNKLASVNDICVQLGLNEVARKAEELMTLFK-GVAATEDMGT 132
            :|||||.|..|.:..:.||.||.||....:.|:.||....|....|.:::..:: .:..|:.:..
Human    69 IKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDL 133

  Fly   133 DTSHPQYATMAVFQACRLLKKKVSKSKLMPFSNLRPSQFQLLEQQWER-----------MIAKHH 186
            |.|.|.:.:.|:..||::||.||.|:|::..|.::.:.|..|.:|.|:           :.....
Human   134 DLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPR 198

  Fly   187 KESKVPSSTDMEGKLKENQNENIKGHEAKKAHKPPPEDYEIWKARMLAKAQAKLK 241
            |..|:.    :|...||.:......|:.:| .:...:|||.||.::|..|.:..|
Human   199 KRKKIV----VEAPAKEMEKVEEMPHKPQK-DEDLTQDYEEWKRKILENAASAQK 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc6	NP_477319.1	Orc6_mid	5..>94	CDD:304498	30/88 (34%)
		Orc6_mid	97..185	CDD:211425	23/99 (23%)
		ORC6_CTD	187..242	CDD:293922	14/54 (26%)
ORC6	NP_055136.1	ORC6	6..>94	CDD:310218	30/88 (34%)
		Orc6_mid	94..186	CDD:211425	23/91 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..232		7/48 (15%)
		ORC6_CTD	199..249	CDD:293922	14/54 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146390
Domainoid	1	1.000	53	1.000	Domainoid score	I11389
eggNOG	1	0.900	-	-		E1_KOG4557
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4957
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45287
OrthoDB	1	1.010	-	-		D1522235at2759
OrthoFinder	1	1.000	-	-		FOG0006558
OrthoInspector	1	1.000	-	-		oto89449
orthoMCL	1	0.900	-	-		OOG6_106334
Panther	1	1.100	-	-	LDO	PTHR13394
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4705
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.800