Sequence 1: | NP_001286256.1 | Gene: | Sting / 36016 | FlyBaseID: | FBgn0033453 | Length: | 343 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001102592.1 | Gene: | Sting1 / 498840 | RGDID: | 1562552 | Length: | 379 | Species: | Rattus norvegicus |
Alignment Length: | 353 | Identity: | 82/353 - (23%) |
---|---|---|---|
Similarity: | 156/353 - (44%) | Gaps: | 77/353 - (21%) |
- Green bases have known domain annotations that are detailed below.
Fly 38 RIVATVFLADLLLRLYRCVVEYGSNGRYYL----PEDRLWIILRRSC-----------TYNN--- 84
Fly 85 RSIYLIVG-------FLLVAFF---RISVTGNYRNVMPTTLFLFQMPLYWIWSFTDMDQSTLSYS 139
Fly 140 H--WIRDSHGLDYAAGMASNYFHGYLKLSLPERKDDGLKHRLAMYEDKNNVTF---GIKRLVIL- 198
Fly 199 -----IPDEMFVNGVLESHLLDKAEP-------LETQFINRAGV-YRPFKHDVYRMNKKVNGRTY 250
Fly 251 YFAV-EGATPMISFFDATYSNLSGTWQMQELKREIWIKFYKHLKELITTWPETRDLVELIIYNSH 314
Fly 315 DSKGNLVDVGELLVAHMQNKTKTIDEIS 342 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Sting | NP_001286256.1 | TMEM173 | 33..335 | CDD:291670 | 80/344 (23%) |
Sting1 | NP_001102592.1 | Mediates interaction with ZDHHC1 and ZDHHC11. /evidence=ECO:0000250|UniProtKB:Q86WV6 | 1..190 | 40/181 (22%) | |
TMEM173 | 44..337 | CDD:291670 | 73/318 (23%) | ||
Cyclic dinucleotide-binding domain (CBD). /evidence=ECO:0000269|PubMed:26669264 | 153..340 | 57/209 (27%) | |||
2',3'-cGAMP binding. /evidence=ECO:0000305|PubMed:26669264 | 162..167 | 1/4 (25%) | |||
2',3'-cGAMP binding. /evidence=ECO:0000305|PubMed:26669264 | 238..241 | 1/2 (50%) | |||
c-di-GMP binding. /evidence=ECO:0000250|UniProtKB:Q3TBT3 | 238..241 | 1/2 (50%) | |||
C-terminal tail (CTT). /evidence=ECO:0000250|UniProtKB:Q86WV6 | 340..379 | 1/3 (33%) | |||
pLxIS motif. /evidence=ECO:0000250|UniProtKB:Q86WV6 | 363..366 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C166338553 | |
Domainoid | 1 | 1.000 | 55 | 1.000 | Domainoid score | I10895 |
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 56 | 1.000 | Inparanoid score | I5341 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D371197at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0008120 | |
OrthoInspector | 1 | 1.000 | - | - | oto96779 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_110638 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR34339 |
Phylome | 1 | 0.910 | - | - | ||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
9 | 8.900 |