DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vamp7 and Vamp7

DIOPT Version :9

Sequence 1:	NP_001286255.1	Gene:	Vamp7 / 36015	FlyBaseID:	FBgn0266186	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_445983.1	Gene:	Vamp7 / 85491	RGDID:	621558	Length:	220	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	113/218 - (51%)
Similarity:	165/218 - (75%)	Gaps:	0/218 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPILYSVISRGTTVLAKFAECVGNFAEVTEHIIGRIGVHNHKMTYTHGDYLIHYTCENKLVYMCI 65
            |.||::|::||||:|||.|.|.|||.||||.|:.:|...|:|:||:||:||.||.|::::||:||
  Rat     1 MAILFAVVARGTTILAKHAWCGGNFLEVTEQILAKIPSENNKLTYSHGNYLFHYICQDRIVYLCI 65

  Fly    66 TDNEFERSRAFLFLADIKQKFIQTYGLQVATAIAYSMNTEFSKILAQQMVYFSQSREVDTISRVH 130
            ||::|||||||.||.::|::|..|||.:..||:.|:||:|||.:||.|:.:.|:::.:|.::...
  Rat    66 TDDDFERSRAFGFLNEVKKRFQTTYGSRAQTALPYAMNSEFSSVLAAQLKHHSENQSLDRVTETQ 130

  Fly   131 GQIDELKDIMVKNIDSLRDRGEKLELLVNKTENLSNNSVAFRKASRNLARQMFWKNIRVYVVVGL 195
            .|:||||.|||:|||.:..|||:||||::|||||.::||.|:..||||||.|..||:::..::.:
  Rat   131 AQVDELKGIMVRNIDLVAQRGERLELLIDKTENLVDSSVTFKTTSRNLARAMCVKNVKLTAIIVV 195

  Fly   196 VITFIVYVIVSMACGGLAWQSCV 218
            |....:|:|||..|||..|.|||
  Rat   196 VSIVFIYIIVSPLCGGFTWPSCV 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vamp7	NP_001286255.1	Longin	32..97	CDD:290490	33/64 (52%)
		Synaptobrevin	122..210	CDD:279324	41/87 (47%)
		R-SNARE_VAMP7	124..188	CDD:277224	36/63 (57%)
Vamp7	NP_445983.1	Longin	4..116	CDD:341428	62/111 (56%)
Vamp7	NP_445983.1	R-SNARE_VAMP7	124..188	CDD:277224	36/63 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350794
Domainoid	1	1.000	99	1.000	Domainoid score	I6917
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4121
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3158
OMA	1	1.010	-	-		QHG53513
OrthoDB	1	1.010	-	-		D1211929at2759
OrthoFinder	1	1.000	-	-		FOG0004661
OrthoInspector	1	1.000	-	-		oto96534
orthoMCL	1	0.900	-	-		OOG6_101193
Panther	1	1.100	-	-	LDO	PTHR21136
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3273
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770