DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vamp7 and VAMP723

DIOPT Version :9

Sequence 1:	NP_001286255.1	Gene:	Vamp7 / 36015	FlyBaseID:	FBgn0266186	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_850201.1	Gene:	VAMP723 / 817873	AraportID:	AT2G33110	Length:	217	Species:	Arabidopsis thaliana

Alignment Length:	211	Identity:	57/211 - (27%)
Similarity:	104/211 - (49%)	Gaps:	6/211 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILYSVISRGTTVLAKFAECVGNFAEVTEHIIGRIGVHNHKMTYTHGDYLIHYTCENKLVYMCITD 67
            :.||.|:|||.:|.:|.:..|||..|....:..:...|:|.||....:..:...||...|..:..
plant     6 LFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAV 70

  Fly    68 NEFERSRAFLFLADIKQKFIQTY-GLQVATAIAYSMNTEFSKILAQQMVY-FSQSREVDTISRVH 130
            :...|.....||..:|:.|.:.| |.:.||..|.|:|.||...|.:.|.| .....|:..:::..
plant    71 DSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAK 135

  Fly   131 GQIDELKDIMVKNIDSLRDRGEKLELLVNKTENLSNNSVAFRKASRNLARQMFWKNIRVYVVVGL 195
            .|:.|:|.:|::||:.:..||...|:|.:.    .:...||......:.|:.:::|:::.::|..
plant   136 AQVSEVKSLMMENIEKVLARGVICEMLGSS----ESQPQAFYIKRTQMKRKKWFQNMKIKLIVLA 196

  Fly   196 VITFIVYVIVSMACGG 211
            :|..::.:|:...|||
plant   197 IIIALILIIILSVCGG 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vamp7	NP_001286255.1	Longin	32..97	CDD:290490	15/65 (23%)
		Synaptobrevin	122..210	CDD:279324	18/87 (21%)
		R-SNARE_VAMP7	124..188	CDD:277224	14/63 (22%)
VAMP723	NP_850201.1	Longin	32..96	CDD:290490	13/63 (21%)
		Synaptobrevin	127..>191	CDD:279324	15/67 (22%)
		R-SNARE	130..184	CDD:277196	13/57 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53513
OrthoDB	1	1.010	-	-		D1211929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21136
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.890