DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vamp7 and VAMP725

DIOPT Version :9

Sequence 1:	NP_001286255.1	Gene:	Vamp7 / 36015	FlyBaseID:	FBgn0266186	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_180826.2	Gene:	VAMP725 / 817827	AraportID:	AT2G32670	Length:	285	Species:	Arabidopsis thaliana

Alignment Length:	212	Identity:	73/212 - (34%)
Similarity:	124/212 - (58%)	Gaps:	4/212 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILYSVISRGTTVLAKFAECVGNFAEVTEHIIGRIGVHNHKMTYTHGDYLIHYTCENKLVYMCITD 67
            ::||.::|||.:|.::.|..|||..|....:.::...|:|.||....:..:|..||...|..:..
plant    71 LIYSFVARGTVILVEYTEFKGNFTAVAAQCLQKLPSSNNKFTYNCDGHTFNYLVENGFTYCVVAV 135

  Fly    68 NEFERSRAFLFLADIKQKFIQTY-GLQVATAIAYSMNTEFSKILAQQMVY-FSQSREVDTISRVH 130
            ....|.....||..:|:.|.:.| |.:..||.|.|:|.||...|.:.|.| .....|:..:::|.
plant   136 ESVGRQIPMAFLERVKEDFNKRYGGGKATTAQANSLNREFGSKLKEHMQYCVDHPDEISKLAKVK 200

  Fly   131 GQIDELKDIMVKNIDSLRDRGEKLELLVNKTENLSNNSVAFRKASRNLARQMFWKNIRV-YVVVG 194
            .|:.|:|.:|::||:.:.|||||:||||:|||||.:.:..||.....:.|:|:::|::: .:|:|
plant   201 AQVTEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTKIRRKMWFENMKIKLIVLG 265

  Fly   195 LVITFIVYVIVSMACGG 211
            ::||.|:.:|:|: |||
plant   266 IIITLILIIILSV-CGG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vamp7	NP_001286255.1	Longin	32..97	CDD:290490	15/65 (23%)
		Synaptobrevin	122..210	CDD:279324	34/88 (39%)
		R-SNARE_VAMP7	124..188	CDD:277224	26/63 (41%)
VAMP725	NP_180826.2	Longin	97..168	CDD:290490	17/70 (24%)
		Synaptobrevin	192..>260	CDD:279324	27/67 (40%)
		R-SNARE	195..253	CDD:277196	24/57 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53513
OrthoDB	1	1.010	-	-		D1211929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21136
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890