DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vamp7 and Sec22a

DIOPT Version :9

Sequence 1:NP_001286255.1 Gene:Vamp7 / 36015 FlyBaseID:FBgn0266186 Length:218 Species:Drosophila melanogaster
Sequence 2:NP_476488.2 Gene:Sec22a / 117513 RGDID:621659 Length:307 Species:Rattus norvegicus


Alignment Length:222 Identity:36/222 - (16%)
Similarity:75/222 - (33%) Gaps:61/222 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 KMTYTHGDYLIHYTCENKLVYMCITDNEFERSRAFLFLADIKQKFIQTYG-LQVATAIAYSMNTE 105
            :.|...|.:.|::.....:.||.:....:....||.||.:::::||.||. ::..||:......|
  Rat    50 RCTLKTGRHNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIE 114

  Fly   106 FSKILAQQMVYFSQSREVDTISRVHGQIDELK----------------------DIMVKNIDSLR 148
            |...:.:....::..|.:.|...:.....|:|                      .:..|....:.
  Rat   115 FDNFIQRTKQRYNNPRSLSTKINLSDMQMEIKLRPPYQIPMCELGSANGVTSAFSVDCKGAGKIS 179

  Fly   149 DRGEKLE------------------------------LLVNKTENLSNNSVAFRKASRNLARQMF 183
            ...::||                              ||.:..|:.| ..:||...:.....|.:
  Rat   180 SAHQRLEPATLSGIVAFILSLLCGALNLIRGFHAIESLLQSDGEDFS-YMIAFFLGTAACLYQCY 243

  Fly   184 -------WKNIRVYVVVGLVITFIVYV 203
                   |:|::.::..||:....:|:
  Rat   244 LLVYYTSWRNVKSFLTFGLICLCNMYL 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vamp7NP_001286255.1 Longin 32..97 CDD:290490 13/55 (24%)
Synaptobrevin 122..210 CDD:279324 18/141 (13%)
R-SNARE_VAMP7 124..188 CDD:277224 15/122 (12%)
Sec22aNP_476488.2 Longin 5..126 CDD:341428 17/75 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5143
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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