DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1663 and LOC680200

DIOPT Version :9

Sequence 1:	NP_610521.1	Gene:	CG1663 / 36012	FlyBaseID:	FBgn0033449	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_038946368.1	Gene:	LOC680200 / 680200	RGDID:	1594231	Length:	491	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	83/337 - (24%)
Similarity:	131/337 - (38%)	Gaps:	68/337 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 YISNQPHKAFYSLQRTSPGVIQYFIQQLRRH---KFFWITEHG--------INKKDRMDSSQKV- 135
            |...:.||:|.|  |:|     .||.| :.|   |.|...|.|        :.:..|:.|.:|:
  Rat   155 YKCKECHKSFSS--RSS-----LFIHQ-KNHTDEKNFKCEECGRSFYYPSMLKQHQRIHSGEKLY 211

  Fly   136 -----AEALFHRFHFQLDPKVVNASARFLQVWFERQY-----------------VMQLSSSDFRC 178
                 .:|.:       ||..:....|...|....:|                 .:......|:|
  Rat   212 KCGECGKAFY-------DPSFLKQHQRIFCVEKHSKYEECGKVFSSALTLNQHKEIHTGEKPFQC 269

  Fly   179 -------RYPKYYHSLLKFMPTNHISVT--ICEECDRRFLNERLLRLHKFRVHGGPNPNVCHVCH 234
                   |:|    |.|:...|.|....  .||||.|.:.:...||.|:. :|...|.|.|..|.
  Rat   270 GKCHKAFRHP----SALRIHMTVHTGEKPYKCEECGRCYFSSLSLRRHQI-IHSEDNSNKCEECG 329

  Fly   235 QSFPLASKLEQHQARYHFKRPEWQCSRCDYNAPSKWDFQQHQAMHAGQRNYICELCGHSSKTSSA 299
            :.|..:|.|.:||. .|.:...::|..|.....|.:..::||.:|:....|.||.|......|::
  Rat   330 RCFSSSSCLRRHQT-IHSEDKTYKCDECGRYYSSSFSLRRHQVIHSEDNPYKCEECDKRFTYSAS 393

  Fly   300 LAVHRRTHDQPK-LCCPHCSRQFRENSTLKSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLHKL 363
            |..|:..|...| ..|.:|.:.||.:|:|:.| :.:|.|.  :...|:.|.|.|.....|:.|:.
  Rat   394 LQEHQTIHTGEKPYKCENCHKAFRHHSSLRKH-KIVHTGE--KPYKCEECGRCFSRYSYLRRHQE 455

  Fly   364 VHLQSEEMESYE 375
            :|.:.......|
  Rat   456 IHSEGNPQTCVE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1663	NP_610521.1	MttA_Hcf106	<33..>91	CDD:294511	2/7 (29%)
		C2H2 Zn finger	201..222	CDD:275368	8/20 (40%)
		C2H2 Zn finger	259..279	CDD:275368	5/19 (26%)
		C2H2 Zn finger	287..307	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..335	CDD:275368	7/20 (35%)
LOC680200	XP_038946368.1	KRAB	2..82	CDD:214630
		SUF4-like	125..>173	CDD:411020	8/24 (33%)
		C2H2 Zn finger	129..150	CDD:411020
		C2H2 Zn finger	129..149	CDD:275368
		COG5048	152..>445	CDD:227381	78/313 (25%)
		C2H2 Zn finger	157..177	CDD:275368	9/27 (33%)
		C2H2 Zn finger	185..205	CDD:275368	3/19 (16%)
		C2H2 Zn finger	213..232	CDD:275368	3/25 (12%)
		C2H2 Zn finger	242..261	CDD:275368	0/18 (0%)
		C2H2 Zn finger	269..289	CDD:275368	6/23 (26%)
		C2H2 Zn finger	297..317	CDD:275368	8/20 (40%)
		C2H2 Zn finger	325..345	CDD:275368	7/20 (35%)
		C2H2 Zn finger	353..373	CDD:275368	5/19 (26%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		C2H2 Zn finger	409..429	CDD:275368	7/20 (35%)
		C2H2 Zn finger	437..457	CDD:275368	6/19 (32%)
		C2H2 Zn finger	465..485	CDD:275368	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100