DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1663 and ZNF691

DIOPT Version :9

Sequence 1:	NP_610521.1	Gene:	CG1663 / 36012	FlyBaseID:	FBgn0033449	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001229668.1	Gene:	ZNF691 / 51058	HGNCID:	28028	Length:	315	Species:	Homo sapiens

Alignment Length:	168	Identity:	57/168 - (33%)
Similarity:	83/168 - (49%)	Gaps:	8/168 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 ICEECDRRFLNERLLRLHKFRVHGGPNPNVCHVCHQSFPLASKLEQHQARYHFKRPEWQCSRCDY 264
            ||.:|.:.|.|...||.|: |:|.|..|..|..|.:||..:|...:|: |.|.:...::|.:|..
Human   116 ICAQCGKTFNNTSNLRTHQ-RIHTGEKPYKCSECGKSFSRSSNRIRHE-RIHLEEKHYKCPKCQE 178

  Fly   265 NAPSKWDFQQHQAMHAGQRNYICELCGHSSKTSSALAVHRRTHDQPK--LCCPHCSRQFRENSTL 327
            :...:.|...||..|.|:|.|.|::||.|...|:.||||.|||.:|.  :|| .|.:.|..:|:.
Human   179 SFRRRSDLTTHQQDHLGKRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICC-ECGKSFSNSSSF 242

  Fly   328 KSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLHKLVH 365
            ..| .:.|.|.  |...|..|.|.|..:.....|:..|
Human   243 GVH-HRTHTGE--RPYECTECGRTFSDISNFGAHQRTH 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1663	NP_610521.1	MttA_Hcf106	<33..>91	CDD:294511
		C2H2 Zn finger	201..222	CDD:275368	8/20 (40%)
		C2H2 Zn finger	259..279	CDD:275368	5/19 (26%)
		C2H2 Zn finger	287..307	CDD:275368	10/19 (53%)
		C2H2 Zn finger	314..335	CDD:275368	5/20 (25%)
ZNF691	NP_001229668.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..90
		COG5048	<108..266	CDD:227381	55/155 (35%)
		C2H2 Zn finger	117..137	CDD:275368	8/20 (40%)
		C2H2 Zn finger	145..165	CDD:275368	7/20 (35%)
		C2H2 Zn finger	173..193	CDD:275368	5/19 (26%)
		C2H2 Zn finger	201..221	CDD:275368	10/19 (53%)
		C2H2 Zn finger	229..249	CDD:275368	6/21 (29%)
		C2H2 Zn finger	257..277	CDD:275368	5/19 (26%)
		zf-C2H2	283..305	CDD:306579
		C2H2 Zn finger	285..305	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3304
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860