DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1663 and Zfp456

DIOPT Version :9

Sequence 1:NP_610521.1 Gene:CG1663 / 36012 FlyBaseID:FBgn0033449 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001001186.3 Gene:Zfp456 / 408065 MGIID:3040694 Length:458 Species:Mus musculus


Alignment Length:361 Identity:92/361 - (25%)
Similarity:145/361 - (40%) Gaps:68/361 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 EVEPNFSPEK----EQGHDELASNSHHDYISNQPHKAFYSLQRTSPGVIQYFIQQ-----LRRHK 114
            :|..:||||:    |....:|..|.   .:.|..|..|..|..:.|.::.:..|:     ::|..
Mouse     6 DVAIDFSPEEWDCLEPAQWDLYRNV---MLENFSHLVFLGLAVSKPFLVTFLEQRQGPWDMKRQG 67

  Fly   115 FFWITEHGINKKDRMDSSQKV-AEALF---HRFHFQLDPKVVNASARFLQVWFERQYVMQLSSSD 175
            ...:.. ||...|..:.|:.. .::|.   .|.|....|.......:.|..........:|.:.|
Mouse    68 MATVYP-GIKPNDPNNFSKLTNCKSLLITQRRNHIGEKPYKCGECGKALSSHKTLSIHQRLHTGD 131

  Fly   176 --FRCRYPKYYH-------SLLKFMPTNHISVTI--CEECDRRFLNERLLRLHKFRVHGGPNPNV 229
              ::|   :..|       ||..:| .||....|  ||:|.|.|....:|:.|: |:|.|..|..
Mouse   132 KPYKC---EECHKAFSTRSSLFIYM-KNHTDEKIYKCEDCGRTFYYLSMLKQHQ-RIHSGEKPYK 191

  Fly   230 CHVCHQSFPLASKLEQHQ---------------------------ARYHFKRPEWQCSRCDYNAP 267
            |..|.:.|...|.|:|||                           .:.|.:...::|..| |.|.
Mouse   192 CEECGKCFGFPSFLKQHQNIHCRKNAYTYEDCVKRLSPPLPLQDNEQIHTEEKPYKCGEC-YKAF 255

  Fly   268 SKWD-FQQHQAMHAGQRNYICELCGHSSKTSSALAVHRRTHDQPK-LCCPHCSRQFRENSTLKSH 330
            |... |:.|:.:|.|:..|.||.||....:||.|..|:..|.:.| ..|..|.|.|..:|:|:.|
Mouse   256 SYHSAFRIHKTVHTGENPYKCEECGKCFSSSSYLKRHQTLHSEDKPYKCEDCGRCFCSSSSLRRH 320

  Fly   331 IRKIH-DGNSARQVSCDFCWRRFKTLELLKLHKLVH 365
             :|.| :||..:   |:.|.:||.....|:.|:.:|
Mouse   321 -QKFHSEGNPYK---CEKCDKRFSCSASLQEHQTIH 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1663NP_610521.1 MttA_Hcf106 <33..>91 CDD:294511 10/35 (29%)
C2H2 Zn finger 201..222 CDD:275368 8/20 (40%)
C2H2 Zn finger 259..279 CDD:275368 7/20 (35%)
C2H2 Zn finger 287..307 CDD:275368 8/19 (42%)
C2H2 Zn finger 314..335 CDD:275368 8/20 (40%)
Zfp456NP_001001186.3 KRAB 2..61 CDD:214630 14/57 (25%)
KRAB 2..41 CDD:279668 10/37 (27%)
C2H2 Zn finger 84..100 CDD:275368 3/15 (20%)
C2H2 Zn finger 108..128 CDD:275368 1/19 (5%)
zf-H2C2_2 121..145 CDD:290200 4/26 (15%)
C2H2 Zn finger 136..184 CDD:275368 16/52 (31%)
zf-H2C2_2 176..199 CDD:290200 8/23 (35%)
C2H2 Zn finger 192..212 CDD:275368 8/19 (42%)
C2H2 Zn finger 248..268 CDD:275368 7/20 (35%)
zf-C2H2 274..296 CDD:278523 9/21 (43%)
C2H2 Zn finger 276..296 CDD:275368 8/19 (42%)
C2H2 Zn finger 304..324 CDD:275368 8/20 (40%)
zf-H2C2_2 316..341 CDD:290200 10/28 (36%)
C2H2 Zn finger 332..352 CDD:275368 6/19 (32%)
zf-H2C2_2 344..369 CDD:290200 3/9 (33%)
C2H2 Zn finger 360..380 CDD:275368
C2H2 Zn finger 388..408 CDD:275368
C2H2 Zn finger 416..436 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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