DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1663 and Zfp58

DIOPT Version :9

Sequence 1:NP_610521.1 Gene:CG1663 / 36012 FlyBaseID:FBgn0033449 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001007576.1 Gene:Zfp58 / 238693 MGIID:99205 Length:489 Species:Mus musculus


Alignment Length:315 Identity:83/315 - (26%)
Similarity:134/315 - (42%) Gaps:60/315 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 EVEPNFSPEKEQGHDELASNSHHD-YISNQPHKAFYSLQRTSPGVIQYFIQQLRRHKFFWITEHG 122
            :|..:||||:.:..:....:.:.| .:.|..|..|..|..:.|.::. |::|             
Mouse     6 DVAIDFSPEERECLEPDQWDLYRDVMLENYSHLDFLGLALSKPFLVT-FLEQ------------- 56

  Fly   123 INKKDRMDSSQKVAEALFHRFHFQLDPKVVNASARFLQVWFERQYVMQLSSSDFRCRYPKYYHSL 187
              ::...|..::.|.|:.       ..|.||....|.:.:|              |:      ||
Mouse    57 --RQGPWDVKRQAAAAVH-------PGKTVNKCKDFSKAFF--------------CK------SL 92

  Fly   188 LKFMPTNHISVTI------CEECDRRFLNERLLRLHKFRVHGGPNPNVCHVCHQSFPLASKLEQH 246
            |    |.|..:..      ||||.:.|.|...|..|| |:|.|..|..|..|.::|.:.|||..|
Mouse    93 L----TQHQRIRTGEKAFKCEECGKAFNNRSNLSEHK-RIHTGEKPYKCEECGKAFRIRSKLSTH 152

  Fly   247 QARYHFKRPEWQCSRCDYNAPSKWDFQQHQAMHAGQRNYICELCGHSSKTSSALAVHRRTHDQPK 311
            | |.|.....::|..|.....|..:..:|:.:|.|::.|.||.||.:..|.|....|::.|...|
Mouse   153 Q-RVHTGEKPYKCEECGKAFNSHSNLSEHKRIHTGEKPYKCEECGKAFSTRSTYYRHQKNHTGKK 216

  Fly   312 -LCCPHCSRQFRENSTLKSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLHKLVH 365
             ..|..|:::|...|.||.| ::||  ::.:...|:.|.:.|....|||.|:::|
Mouse   217 PYKCEECAKEFSYPSLLKVH-QRIH--SAEKSYKCEECGKPFYCPLLLKKHQIIH 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1663NP_610521.1 MttA_Hcf106 <33..>91 CDD:294511 8/32 (25%)
C2H2 Zn finger 201..222 CDD:275368 10/20 (50%)
C2H2 Zn finger 259..279 CDD:275368 4/19 (21%)
C2H2 Zn finger 287..307 CDD:275368 7/19 (37%)
C2H2 Zn finger 314..335 CDD:275368 7/20 (35%)
Zfp58NP_001007576.1 KRAB 2..61 CDD:214630 13/70 (19%)
KRAB 2..41 CDD:279668 8/34 (24%)
C2H2 Zn finger 80..100 CDD:275368 8/43 (19%)
COG5048 106..489 CDD:227381 56/168 (33%)
C2H2 Zn finger 108..128 CDD:275368 10/20 (50%)
zf-H2C2_2 120..143 CDD:290200 9/23 (39%)
C2H2 Zn finger 136..156 CDD:275368 9/20 (45%)
zf-H2C2_2 149..173 CDD:290200 7/24 (29%)
C2H2 Zn finger 164..184 CDD:275368 4/19 (21%)
zf-H2C2_2 176..201 CDD:290200 8/24 (33%)
C2H2 Zn finger 192..212 CDD:275368 7/19 (37%)
C2H2 Zn finger 220..240 CDD:275368 7/20 (35%)
C2H2 Zn finger 248..268 CDD:275368 7/19 (37%)
C2H2 Zn finger 276..296 CDD:275368
C2H2 Zn finger 304..324 CDD:275368
C2H2 Zn finger 332..352 CDD:275368
zf-H2C2_2 344..369 CDD:290200
C2H2 Zn finger 360..380 CDD:275368
C2H2 Zn finger 388..408 CDD:275368
C2H2 Zn finger 412..432 CDD:275368
zf-H2C2_2 424..449 CDD:290200
C2H2 Zn finger 440..460 CDD:275368
C2H2 Zn finger 468..488 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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