Protein Alignment CG1663 and ZNF689

DIOPT Version :10

• Sequence 1: NP_610521.1
• Gene: CG1663 / 36012
• FlyBaseID: FBgn0033449
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_612456.1
• Gene: ZNF689 / 115509
• HGNCID: 25173
• Length: 500
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 70/199 - (35%)
• Similarity: 98/199 - (49%)
• Gaps: 12/199 - (6%)

  Fly   170 QLSSSDFRCRYPKYYHSLLKFMPTNHISVT--ICEECDRRFLNERLLRLHKFRVHGGPNPNVCHV 232
            |..|...|..||    |||......|....  .|.||:|||.....|.:|: |:|.|..|..|..
Human   262 QCPSCGRRFAYP----SLLAIHQRTHTGEKPYTCLECNRRFRQRTALVIHQ-RIHTGEKPYPCPD 321

  Fly   233 CHQSFPLASKLEQHQARYHFKRPEWQCSRCDYNAPSKWDFQQHQAMHAGQRNYICELCGHSSKTS 297
            |.:.|..:|:|..|:..:..:|| :.|..|:.....:....|||.:|.|::.|.|..||.:.:.|
Human   322 CERRFSSSSRLVSHRRVHSGERP-YACEHCEARFSQRSTLLQHQLLHTGEKPYPCPDCGRAFRRS 385

  Fly   298 SALAVHRRTHDQPKL-CCPHCSRQFRENSTLKSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLH 361
            .:||:||.||.:.|| .|..|.|:|...|.|.|| |::|.|.  |..:||.|.:||.....|..|
Human   386 GSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASH-RRVHSGE--RPYACDLCSKRFAQWSHLAQH 447

  Fly   362 KLVH 365
            :|:|
Human   448 QLLH 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1663	NP_610521.1	C2H2 Zn finger	201..222	CDD:275368	9/20 (45%)
		C2H2 Zn finger	259..279	CDD:275368	5/19 (26%)
		C2H2 Zn finger	287..307	CDD:275368	8/19 (42%)
		C2H2 Zn finger	314..335	CDD:275368	9/20 (45%)
ZNF689	NP_612456.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		KRAB	29..88	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..146
		C2H2 Zn finger	151..171	CDD:275368
		COG5048	159..>466	CDD:227381	70/199 (35%)
		C2H2 Zn finger	179..199	CDD:275368
		C2H2 Zn finger	207..227	CDD:275368
		C2H2 Zn finger	235..255	CDD:275368
		C2H2 Zn finger	263..283	CDD:275368	7/23 (30%)
		C2H2 Zn finger	291..311	CDD:275368	9/20 (45%)
		C2H2 Zn finger	319..339	CDD:275368	6/19 (32%)
		C2H2 Zn finger	347..367	CDD:275368	5/19 (26%)
		C2H2 Zn finger	375..395	CDD:275368	8/19 (42%)
		C2H2 Zn finger	403..423	CDD:275368	9/20 (45%)
		C2H2 Zn finger	431..451	CDD:275368	8/19 (42%)
		C2H2 Zn finger	459..475	CDD:275368