Protein Alignment dila and cep131

DIOPT Version :10

• Sequence 1: NP_001137629.2
• Gene: dila / 36010
• FlyBaseID: FBgn0033447
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_012822162.2
• Gene: cep131 / 734011
• XenbaseID: XB-GENE-1016768
• Length: 1095
• Species: Xenopus tropicalis
• Alignment Length: 1262
• Identity: 284/1262 - (22%)
• Similarity: 529/1262 - (41%)
• Gaps: 292/1262 - (23%)

  Fly     2 DLCLKGSQVSSERHGLPPFGLGTKSGQPQINLAT--RQKTKPKYTSRSLTTLHNPCPHFRPRSAN 64
            ||.|.|||||..|.  |.....||.....|::.|  |.|..|...|              ||:.|
 Frog    18 DLALTGSQVSVTRR--PSSAGSTKHITRSISVITDCRSKGNPLKDS--------------PRAIN 66

  Fly    65 FLQQRSRSSPFLGRPQSADPKFGRRLSNYFVEKELRNGGKRQVSSNDLLKSLLEEPIKRSW---- 125
            .| :||.|:..:  |......|......:....|..:.|::::.|  |:|:..|:  |.:|
 Frog    67 NL-RRSNSTTQV--PPENSSAFRDHQDEFLAFFESSSIGRKKLDS--LVKTSPEK--KTTWNILD 124

  Fly   126 ------LCRSTCNSSESDYSLHKRTPDSSEEGEQFLVNM-----PVGEKVKS--YSSY-SGNQGL 176
                  ...|:..||.|...|..:..|:......|..|.     .||..|.:  :::| :|.:||
 Frog   125 DQPRVFPVPSSARSSSSAQGLSLKKRDTPALAPSFPANNRSNKGAVGNMVTTMVHNNYAAGERGL 189

  Fly   177 SNGALLQRTAKPDLPGRVSFSKPNMHADLDSSDCDNDKQEVRPSISAPGPLTLPSFLSKVEQADP 241
            ||.:..||.|..:     :...|.:      .|..:..|:.:.::|               .|:.
 Frog   190 SNKSSNQRPASLN-----NLRSPGV------EDSGSSFQKSQKNLS---------------NANN 228

  Fly   242 VGQKKSVHFGSTAAEGEVLAETYEYPKCPSENCTCSTRSSSTTSTNEASASDVKCACDAPSCRFM 306
            :| :.:...|:.....||.||..|                                      ||:
 Frog   229 LG-RNNAGGGTPPKRKEVTAEEAE--------------------------------------RFI 254

  Fly   307 ESSKQVEPTSPTPTLPKAPSSELDVIREYKQAVEGVQVVKNHLGTDTLNNIEILPNYLDKYASPT 371
            :   ||...:.|            :.|.|::     |..|...|.:.|.::         .||..
 Frog   255 Q---QVNNAAVT------------IQRWYRR-----QWQKRRSGEEALKHL---------MASKK 290

  Fly   372 KEKQNNLSETKNMATNSSAVNNGSVVYRPVGNPRNFGAENNFLPAVQDDRRSFANGSSDGVINNY 436
            :|:|.::.|...:....|....    .|.|...:...|....:..:|..|...|..:...|....
 Frog   291 EERQQHMEEGNLLTPQQSREEE----RRRVREEKARQARRAAIQELQQKRSQKALETQQLVEEEI 351

  Fly   437 LKVASTPPFVGKKKENVKPASADPIARSSKSKVTKSTINPAPLGKMKKAISVGSLREERKLSEYN 501
            .::..... ||:||....|.|                   :|||...||.:.||    |..:|.|
 Frog   352 HRLVQNGK-VGRKKTVKNPVS-------------------SPLGNRTKANNTGS----RIQTEIN 392

  Fly   502 LDKVDSWMSM----------QDQK-QYDGKHKPGLEDLDEAQDNDTASQLSLKSNEDSRDSTYDE 555
            .:  |:.:.|          ::|| |.....:....|||          :...::.....:|..|
 Frog   393 QE--DAGVLMFSPAPENNKDEEQKIQVSSHAEQTFRDLD----------IEFSASRAQSKTTLTE 445

  Fly   556 IVSVIKEIE----------EDKKRDNFSEG-IPSELNL-NLD---------SRCETADTVTVSEG 599
            ::..::::|          |.|.:..|.:| |.|.|.: ||:         .|.|..:.|.:||.
 Frog   446 LLDTLRQLEEPEPLPEIKSEPKDKYQFIDGDIDSSLTVDNLERLGQLTHNGERKEEINGVLLSEA 510

  Fly   600 KVPESGDKYKDILAYLNNVESSCDKTLMETRRSIPDSNRSEVEFVVEPDVTDEVPKLSELLMLPN 664
            |:       :.|:::|:.:|.|    ..|..||.. ||..:...:.|.::| .:.:.|.:..
 Frog   511 KL-------QSIISFLDEMEIS----EQERPRSAA-SNTQKGALLSEEELT-HLEQASAVAT--- 559

  Fly   665 HQLARRVIALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKST---AAAKLRDQKKHYEEVVT 726
             ::...::.|.|...|...|:::.:..:.|   :::.::|..|.|   ...:|:.|.:.||..:.
 Frog   560 -EVTSSMLKLRLEVQEKTRALNLLQTALAQ---QRELTVRHAKQTEKELGQQLKQQGEQYEATIQ 620

  Fly   727 RHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLE-----------------TELARTKET 774
            ||..||:||:.||.:|.|:..:|.:.|:..:|.:..::.                 .|:.:.::.
 Frog   621 RHLSFIDQLIDDKKALSERCESLVKELKQVDQKYSSKISQMQEQHEMVWQTLGPLCEEMKKLQDL 685

  Fly   775 TMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKH 839
            ..|.||:|||:|:.|.||||||:||||||.||.::...|::|:.:||..|:.:|..:.|.|..::
 Frog   686 MSATEKVRREKWIDEKTKKIKEITVKGLEPEIQRLISKHKQEIRKLKALHEAELQQSDERAAQRY 750

  Fly   840 EQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRL-QSELR 903
            .:....:|.:..:::|.:.::||...::|:|:.|.:|:::..|||::|.:|.:.|::|| |...|
 Frog   751 VRQTEEMRHNLEREKEEVSQRERELAKQRYEKHLVQEEQSLQEQRRRLFQEVSEEKERLNQQAAR 815

  Fly   904 QRENEHQARRQ------EALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKT 962
            ||....:.|:|      .|.|..::|.|::|.|       ||.::|..:..::::.:.:.:.|:.
 Frog   816 QRAELDELRKQLEDNCALATRVLKEEYEKSKDE-------QERRHQAEIKALKERLEIEKQAWEQ 873

  Fly   963 EHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHEL----KMNRLKEKYEKD 1023
            .:..|.:.....:|..:::..|..|||:::.::.|:|::....|:|.|.    ::.|:::|||.:
 Frog   874 NYMKKEETWLLSRERELKEDVRKGRDREIELVIQRLESEMSTAKDECERACENRIKRIRDKYESE 938

  Fly  1024 LVLAESVEKSLREKYAETRGKLAEADAQ-------VRNSQAEVKQLQL---ELSHSKKMCGDIIM 1078
            |...|..|:.|:|:..:.:.::.|.:.:       :|..:.|::.::.   .||..:|...::|.
 Frog   939 LQELERSERKLQERCNQLKEQVTELEGEQIRLQGLLRQKEQEIEDIRKVTDRLSEERKSLSEVIR 1003

  Fly  1079 ER--DRL----RDNLNADIQS---------ELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILK 1128
            :.  |||    .:|.....::         ||..:|....:|::::.|||...|.::|||:..|:
 Frog  1004 QEFADRLVLTEEENRRLKTEASEARARQRLELERVNREKDEELEEVHKRVKTAIVKKEETVNSLR 1068

  Fly  1129 GDNDALRQQCLKLNAVIRQQRKDYCVK 1155
            ...:|..::...|.|::.||||....|
 Frog  1069 KQCEAAVKRADHLEALLEQQRKQLLAK 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dila	NP_001137629.2	EnvC	700..>941	CDD:443969	81/267 (30%)
		Smc	<827..>1066	CDD:440809	58/259 (22%)
		GumC	<999..>1150	CDD:442439	41/179 (23%)
cep131	XP_012822162.2	PTZ00121	<273..1009	CDD:173412	185/811 (23%)
		Smc	<726..>1047	CDD:440809	74/327 (23%)