Protein Alignment CG1698 and SLC6A7

DIOPT Version :9

• Sequence 1: NP_001260835.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Alignment Length: 677
• Identity: 232/677 - (34%)
• Similarity: 349/677 - (51%)
• Gaps: 95/677 - (14%)

  Fly    25 ASTISIP---GAYKP-NESSNGKKTLSEGSGSAPP----PGHGDSP----SGVEAGQP------- 70
            |:..|:|   ||.:| .:..:|::|:|.......|    |||..|.    .|....:|
Human    36 AAPASVPAPAGAREPRGQRRSGQRTISRALALCAPGQLSPGHPLSKMKKLQGAHLRKPVTPDLLM 100

  Fly    71 --------------GKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLI 121
                          ...|.:|...::||:|||...||||||||||:.|..||||||::||.::|.
Human   101 TPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLA 165

  Fly   122 LVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFY 186
            :.|.|:::||:.||||||.|.:.|:..||:.:|.|...:|..|:|..||..::|..|.|...|..
Human   166 ICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLT 230

  Fly   187 PTLPWSYCREEWGTE-CLD-------------------------------SGPQEASRATSLAGS 219
            ..|||.:|...|.|| ||:                               ...:|..|...::.|
Human   231 SDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRRGRVVSNS 295

  Fly   220 GVRT------TSAEFYFTNIILREKASIDDGIGYPS---WSLALALAVAWIVIAGIMFKGVKSSG 275
            ..:.      ..||...:..:|..:.|  .|||.|.   |:|.|.|.:||:::...:.|||||||
Human   296 YPQVIFLPQPPKAEEGVSRYVLHIQGS--QGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSG 358

  Fly   276 KASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGN 340
            |..||.|.|||:::|:||||.:|||||:.|:.::|.||:|.||..:||..|..|:|:||.:.||.
Human   359 KVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGG 423

  Fly   341 IIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFI 405
            ::.:||||.|..|||||..|||..:..||:|:|..||.:||.::.|.. ..:..|...||||||:
Human   424 LLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELG-VPVDQVAKAGPGLAFV 487

  Fly   406 SYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFG-HLKNWTVVVG--IAIV 467
            .||.|:......| .:|.|||.||..||:.|.......:.|.:.|:|. :|:....|..  |.:.
Human   488 VYPQAMTMLPLSP-FWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVA 551

  Fly   468 GYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYY 532
            .|.:||:..|.||.:.|.|:|.:..:|..:|:.|...:.:..:||::|.|||:..|:|.|..||:
Human   552 MYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYF 616

  Fly   533 RICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPA------ 591
            |.||..::|..:|.:::|::|.|:|.:|..|.:.....:.|..:     |.:....|||
Human   617 RACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILM-----GLLSCLMIPAGMLVAV 676

  Fly   592 VRKQPSHLGLWARIRKAFEPLPNWGPS 618
            :|::.|   ||.|:::|..|..:||||
Human   677 LREEGS---LWERLQQASRPAMDWGPS 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	194/520 (37%)
SLC6A7	XP_016865256.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920