DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and si:ch211-132b12.2

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001038688.1	Gene:	si:ch211-132b12.2 / 571877	ZFINID:	ZDB-GENE-050420-178	Length:	582	Species:	Danio rerio

Alignment Length:	547	Identity:	183/547 - (33%)
Similarity:	314/547 - (57%)	Gaps:	27/547 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQ 136
            ::|.:|.:..||:::...:.:|||||||||:...:||||||::|||:.::..|.|::.||..:||
Zfish     9 EERGNWGSKTEFILAVAGIVIGLGNVWRFPYLCYKNGGGAFLVPYLVFVVTCGVPLFLLETAMGQ 73

  Fly   137 FSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT 200
            ::..|.:..:. ..|:..||||...|.......||..::|..|.|...||...|||:.|...|.|
Zfish    74 YTQEGGITCWHRLCPLAEGIGYAGQLIVLYSCMYYIIILAWALFYLAFSFSSQLPWASCDNIWNT 138

  Fly   201 E-CLDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIA 264
            : |::....:.:.:|.:..:.  |:|...::.:.:|.....|:. :|..:|.:.|.|.|.||:..
Zfish   139 DACVNLAENKLNLSTPMLLNS--TSSVTEFWQHRVLALSGGIEK-VGKINWEILLCLIVMWIICY 200

  Fly   265 GIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQ 329
            ..::|||||:||..||.|.||||::||||:|.||||||..||:::|.|:..:|.:||||..|..|
Zfish   201 FCVWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPARLADPQVWMEAGAQ 265

  Fly   330 VFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIAS 394
            :|||.|:...::.:..|||::.:|.||.:..:..|::.||:::|..:|.:||.:| :.....|..
Zfish   266 IFFSYALGTASLTVLGSYNKYNYNCYRSSLWLCLLNSSTSVIAGFAVFSVLGFMA-QKQGLPIEE 329

  Fly   395 VVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSN-VGMASCMSTVIKDQF------ 452
            |...|||||||:||.|:|...: |||::..||:|:.:||:.:. |.|...|::|| |.|
Zfish   330 VAESGPGLAFIAYPQAVAMMPF-PQLWAACFFIMIILLGLDTQFVAMEVFMTSVI-DLFPTVLRK 392

  Fly   453 -GHLKNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALV-LAIFELVTIAWIYGVKR 515
             |..:.:.::  ..:..:|..|:.:|.||.::..|.||:..:...|: |.:||.:.:.|::|.::
Zfish   393 AGRREIFLLL--FCLFCFFGQLVMVTEGGMYVFQLFDYYACSGACLLFLCVFESLAMGWVFGAEK 455

  Fly   516 LCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKY-KDYTYQSGVYVFGWCLSAF 579
            :...:|.|...:.:.::.:||..:||::.|...:.:||.|:||.: :.|.|....||.||.|:..
Zfish   456 MFGIIEDMTNSRPNYWFMLCWKYLTPIVSLASFVCSLVKYKPLTFNRWYVYPDWAYVLGWLLALS 520

  Fly   580 GVGQVLFWAI-------PAVRKQPSHL 599
            .:..|..||:       .:::::.|||
Zfish   521 SILLVPGWALGRMFAGKGSIKQRWSHL 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	164/487 (34%)
si:ch211-132b12.2	NP_001038688.1	SLC6sbd-TauT-like	11..550	CDD:271387	183/545 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820