Protein Alignment CG1698 and Slc6a12

DIOPT Version :10

• Sequence 1: NP_610517.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_059031.1
• Gene: Slc6a12 / 50676
• RGDID: 620255
• Length: 628
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 221/570 - (38%)
• Similarity: 322/570 - (56%)
• Gaps: 35/570 - (6%)

  Fly    72 KKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQ 136
            |.|..|.|.:||::|.....:|||||||||:...:||||||.|||.|.....|.||::||:.|||
  Rat    48 KDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQ 112

  Fly   137 FSSRGSVKVY-DFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT 200
            :||:|||..: ...|:::|||...|:....:..||..::|..|.|...||...|||:.|...|.|
  Rat   113 YSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNT 177

  Fly   201 E-CLDSGPQEASRATSLAGSGVRTTSAEFYFTNIIL----REKASIDDGI---GYPSWSLALALA 257
            | |:|.....::||.|.:.:          ||:.::    |....|..||   |...|.|||.|.
  Rat   178 EHCVDFLNYSSTRAASYSEN----------FTSPVMEFWERRVLGITSGIHDLGSLRWELALCLL 232

  Fly   258 VAWIVIAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQV 322
            :|||:....::|||||:||..||.|.|||:::::||:|.:|||||:.|::::|:|...:|.:|||
  Rat   233 LAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQV 297

  Fly   323 WYAAVTQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYEN 387
            |..|.||:|||.|||.|.:....|||::.:|.|||:..:..|::.||.::|.::|.|||.:|.|.
  Rat   298 WMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMAQEQ 362

  Fly   388 NTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQF 452
            . ..|:.|...|||||||::|.|:.... |.||:|.||||||..||:.|......|:.|...|.|
  Rat   363 G-VPISEVAESGPGLAFIAFPKAVTMMP-LSQLWSCLFFLMLLFLGLDSQFVCMECLVTASMDMF 425

  Fly   453 GHL-----KNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALV-LAIFELVTIAWIY 511
            ...     :...:::.:|||.|.:|||.:|.||.::..|.||:..:.:.|: |::||::.|.|:|
  Rat   426 PQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVY 490

  Fly   512 GVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKD-YTYQSGVYVFGWC 575
            |..|...:||.|||.:.....:|.|..:||.|.|....::|..|.||||.: |.|.|..|..||.
  Rat   491 GADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYIYPSWGYSIGWL 555

  Fly   576 LSAFGVGQV-LFWAIPAVRKQPSHLGLWARIRKAFEP---LPNWGPSDPQ 621
            |:...:..| ||..|..::.|.|   ...|:::...|   ||..|...||
  Rat   556 LAFSSMACVPLFIIITLLKTQGS---FKKRLQRLITPDPSLPQPGRRSPQ 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_610517.1	SLC6sbd	75..552	CDD:271359	193/491 (39%)
Slc6a12	NP_059031.1	SLC5-6-like_sbd	49..589	CDD:444915	214/554 (39%)