Protein Alignment CG1698 and slc6a5

DIOPT Version :9

• Sequence 1: NP_001260835.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001009557.1
• Gene: slc6a5 / 494450
• ZFINID: ZDB-GENE-050105-2
• Length: 786
• Species: Danio rerio
• Alignment Length: 711
• Identity: 246/711 - (34%)
• Similarity: 376/711 - (52%)
• Gaps: 108/711 - (15%)

  Fly    12 NGYMNQAYVGSLNASTISIPGAYKPNESS---------------------------NGKKTLSEG 49
            |..:.:..||.::|||......:..|..|                           :|..::..|
Zfish    84 NSAVRKDSVGKMDASTGKATSDFMSNNQSAVRIAAEHNNSTGDWTSMSQTTIILGTDGNTSVLPG 148

  Fly    50 SGSAPPPG-------HGDSPSGVEAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALEN 107
            :.:.||..       ..|...|   |...|.|.:|:|.::|::|.:..:||||||||||:.|.:|
Zfish   149 TVTGPPTDDTGRLFQDDDDDDG---GDENKARGNWSNKLDFILSMVGYAVGLGNVWRFPYLAFQN 210

  Fly   108 GGGAFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYAT 172
            |||||:|||||:|.|.|.|::.||:.||||:|:|.|.|:...|.::|.|...::.:.::..||..
Zfish   211 GGGAFLIPYLIMLGLAGIPIFLLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNI 275

  Fly   173 LMALTLRYFVDSFYPTLPWSYCREEWGT-EC-------LDSGPQEASRATSLAGSGVRTT----- 224
            :|..||.|...|...||||:.|:.||.| ||       ||:........||:.    .||
Zfish   276 IMCWTLYYLFASLKETLPWATCKNEWNTVECKDKDMLLLDTCILRDRNITSIK----NTTFCLSA 336

  Fly   225 ----------------------SAEFYFTNIILREKASIDDGIGYPS---WSLALALAVAWIVIA 264
                                  |.|::..|::     .|..||.||.   |.||..|.:||:::.
Zfish   337 NVVGNLSKLLNVTVDNKTYVSPSEEYFKYNVL-----HISKGIEYPGDIRWPLAACLFLAWLIVY 396

  Fly   265 GIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQ 329
            ..:.||:|||||..||.|.|||||:::||:|.:|||||..|:|||:.|:|.||.:.:||..|.||
Zfish   397 ASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGSGILYFITPKWEKLNDAKVWKDAATQ 461

  Fly   330 VFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIAS 394
            :||||:..:|.:|..:|||:|.:|.|||..|||..::.||:.:|.:||.::|.:|:|.. ..|.|
Zfish   462 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMAHELK-VPIES 525

  Fly   395 VVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQF-----GH 454
            |.:.|||:||:.||:|:.:....| .::::|||||..||:.:.......:.|.:.|:|     .|
Zfish   526 VADEGPGIAFVVYPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSVSDEFPKYLRKH 589

  Fly   455 LKNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRD 519
            ...:|:|..::.  :.||...||..|.::|.|||.|..::..:::||||||.|::|||::|.|.|
Zfish   590 KPQFTLVCCLSF--FVLGFPMITESGMYMLQLVDTFAASYSLVIIAIFELVGISYIYGLQRFCED 652

  Fly   520 VEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQV 584
            :|.|||.:.:.::|:|||.|||.::..||..:|..::.:.|:||||.:...|.||.:....|
Zfish   653 IEMMIGFQPNKFWRVCWAFVTPTILTFILALSLYQWKVMTYEDYTYPNWSMVLGWLMVICSV--- 714

  Fly   585 LFWAIPAVRKQPSHL---GLWARIRKAFEPLPNWGPSDPQTLK----RYQLFVQEGNANAL 638
             .| ||.:.....||   .|..|::....|.|:|||.   .:|    ||:..:.....|:|
Zfish   715 -IW-IPIMFAIKMHLAPGSLIERLKLVCSPQPDWGPF---LMKHRGERYKNMIDPLGTNSL 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	202/519 (39%)
slc6a5	NP_001009557.1	SLC5-6-like_sbd	177..775	CDD:294310	230/615 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920