DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and CG4476

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_648293.1	Gene:	CG4476 / 39056	FlyBaseID:	FBgn0035969	Length:	629	Species:	Drosophila melanogaster

Alignment Length:	626	Identity:	380/626 - (60%)
Similarity:	477/626 - (76%)	Gaps:	28/626 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SGSAPP------PGHGDS-------PSGVEAGQ--PGKK-RDSWNNDIEFLMSCIALSVGLGNVW 98
            ||..|.      .|.|::       |..:|:.:  |.:| ||:|.:.:|||||||||||||||||
  Fly    11 SGGLPKLETSRCAGSGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVW 75

  Fly    99 RFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLAT 163
            ||||||||||||||:||||:||.:||||:||:|||||||||||.|:|:||:|:|||:||.|:||.
  Fly    76 RFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAPLMRGVGYAQLLAL 140

  Fly   164 GIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGTECLDSGPQEASRATSLAGSGVR--TTSA 226
            |::.||||::||||||||.|||...||||:||||||..|:     .||....|.|...|  ::|.
  Fly   141 GVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGCV-----SASGGQPLQGQLSRNFSSST 200

  Fly   227 EFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVMLV 291
            :.|...|:|.|..|:::||||||.||||.|.::|:.:..|:.:||||||||:|.|||||||||.:
  Fly   201 QLYLQRIVLNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFI 265

  Fly   292 LLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNIYR 356
            |||||||||||:|||:|||.|||.|||||||||.||||||||||:|||.||||:||||||||:||
  Fly   266 LLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYR 330

  Fly   357 DANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLF 421
            ||||||||||||||||||||||||||||:|:.|.||||||..|||||||||||||||||..||:|
  Fly   331 DANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVF 395

  Fly   422 SVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHLKNWTVVVGIAIVGYFLGLLYITPGGQFLLNL 486
            |:|||.|||:||:||||||.||:.||:||||.::|.|.:||.::::|:.:||:|||||||.::.|
  Fly   396 SLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLWIIVVSLSVIGFLVGLIYITPGGQHIITL 460

  Fly   487 VDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYT 551
            :|:.|||||:||.|||||:.:.||||.||||:|.|:|:.||||.||||||::||||:||.||:|:
  Fly   461 MDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYS 525

  Fly   552 LVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWG 616
            |:...||.|....:.....|.|||:|...:||:.:||..|..|||.. .|.:||..:.:|..:||
  Fly   526 LLTMRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFKQPKG-SLKSRINNSIKPHSDWG 589

  Fly   617 PSDPQTLKRYQLFVQ---EGNANALFRRSSIWHKIYDNIFG 654
            ||||:.|..||:|::   |.|:..:.|| .:.:...|.|||
  Fly   590 PSDPKKLMDYQMFLRNKDEENSKNVNRR-CVCYTAGDRIFG 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	331/478 (69%)
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	331/478 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14202at7147
OrthoFinder	1	1.000	-	-		FOG0008552
OrthoInspector	1	1.000	-	-		otm50622
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13521
	8	7.850