DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and DAT

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001261026.1	Gene:	DAT / 36849	FlyBaseID:	FBgn0034136	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	582	Identity:	208/582 - (35%)
Similarity:	322/582 - (55%)	Gaps:	54/582 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SGSAPPPGHGDSPSGVEAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVI 114
            |.|..|..|.:..:.:     ..:|::|:..::||:|.|..:|.|.||||||:...:||||||::
  Fly     8 SKSKTPTPHDNDNNSI-----SDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLV 67

  Fly   115 PYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYYATLMALTL 178
            ||.|:|::.|.|::|:|:.|||.:.:|::..:. ..|:.:||||..||....|..||..::|.:|
  Fly    68 PYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSL 132

  Fly   179 RYFVDSFYPTLPWSYCREEWGT-ECLDSGPQEASRA---------------------TSLAGSGV 221
            |:|..||..:|||:.|...|.| .|.....|.|||.                     |.:.||.:
  Fly   133 RFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSL 197

  Fly   222 RT----------TSAEFYFTNIILREKAS--IDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSS 274
            .|          ::|..||...||....|  |.| :|...|.:||.|.:.:::....::||:.:|
  Fly   198 DTSAVGHVEGFQSAASEYFNRYILELNRSEGIHD-LGAIKWDMALCLLIVYLICYFSLWKGISTS 261

  Fly   275 GKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFG 339
            ||..:|.|||||.|:|:||:|.|||||:|.|:.|:|.|.:..:.:.:||..|.|||||||...||
  Fly   262 GKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFG 326

  Fly   340 NIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAF 404
            .::.|||||::.:|:|:||.:.:.:::.||.::|.:||.:||.:|:..... |..|...||||.|
  Fly   327 VLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVR-IEDVATEGPGLVF 390

  Fly   405 ISYPDAIAKFKWLP--QLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHLK--NWTVVVGIA 465
            :.||.|||.   :|  ..::::||:||..||:.|:.|.:..:.|.:.|:|..:|  ....|.|:.
  Fly   391 VVYPAAIAT---MPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLF 452

  Fly   466 IVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSL 530
            .:.:.:||...|.||.:..:|:|.:...:..||...||.:.::||||..|...|:..|||.....
  Fly   453 SLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGR 517

  Fly   531 YYRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAV 592
            |:::||..|.|:.:|.|.:|.|:.||||.|.||.|.|.....|||::...|..     ||||
  Fly   518 YWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVM-----IPAV 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	185/515 (36%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	204/558 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440749
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850