DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and CG13793

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	635	Identity:	148/635 - (23%)
Similarity:	281/635 - (44%)	Gaps:	119/635 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLL 134
            |...|.:|....:::.:|..|::.| :::...|....|.|...::|||:.:::...|:..:...:
  Fly     8 PDLNRGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYM 71

  Fly   135 GQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCR--EE 197
            |||||.|.:..:..||:.:|:||..:..|..:..||....|:.|.:.::||.|||||| |.  :.
  Fly    72 GQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEGFKS 135

  Fly   198 WGTE-------CLDSGPQEASRATSLAGSGVRTTSAEFYFTNI-------------ILREKASID 242
            |..:       |..:..:|.::.|.        ....||.|||             ..:..:.::
  Fly   136 WQNDTIAKWSICNATIAEEVAKETE--------NDTYFYITNIHVPSVLYFKSHFESFQNDSELN 192

  Fly   243 DGIGYP-SWSLALALAVAWIVIAGIMFKGVKSS--GKASYFLALFPYVVMLVLLVRALTLPGAFD 304
            |   |. ||.|:...|:.|..||.|.:|..:.:  ||...::.:....::||..||.|.||||..
  Fly   193 D---YEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHL 254

  Fly   305 GVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAI-----CFGNIIMYASYNRFGHNIYRDANIVTTL 364
            |:..::.|...:       :...|...|.:|:     .:|::|..:|:|.|..||...:.|::..
  Fly   255 GLKNYMTPSIEE-------FVVGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYSWIISFG 312

  Fly   365 DTFTSLLSGVIIFGI------LGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLFSV 423
            ..|..::.|::.|.:      |....:|      ..|:|  ..:.|:|...|::...| |.|::.
  Fly   313 QIFIYIMFGMVSFMLEHYFLGLPKPLFE------TQVIN--HWVLFLSSASALSSLGW-PNLWTF 368

  Fly   424 LFFLMLFVLGIGSNVGMASCMSTVIK---DQFGHLKNWTVVVGIAIVG-------YFL---GLLY 475
            :::.||.:..:   :.:.:.:.|:::   |:|..|:.....|.:.::|       ||.   |:||
  Fly   369 IYYTMLLMAAL---IVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYFCTNHGVLY 430

  Fly   476 ITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVT 540
            ..     :|::...|..|.:.|:|    |:.:.|:||..|..:|::||:|...:.:.......|.
  Fly   431 FA-----ILSIDAIFSQTLLHLLL----LLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVA 486

  Fly   541 PLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPA-----VRKQPSHLG 600
            |    ..|:..|||...:..::::|.|.|..|   ::...||..:. ||||     :.::|..:.
  Fly   487 P----PTLVICLVLEIKMCLEEHSYSSSVLHF---MAIILVGLPIL-AIPAYGFYYIHQRPGSIS 543

  Fly   601 LWARIRKAFEPLPNWGPSDPQTLKRYQLFVQEGNANALFRRSSIWHKIYD 650
            ...|       ..:|.|.:.:..::|...||         :|.:.|:::|
  Fly   544 ELFR-------ATDWYPVEMEYRQQYGELVQ---------KSEMTHQLFD 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	123/525 (23%)
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	125/523 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440775
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840