DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and ine

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001162871.1	Gene:	ine / 33659	FlyBaseID:	FBgn0011603	Length:	943	Species:	Drosophila melanogaster

Alignment Length:	628	Identity:	210/628 - (33%)
Similarity:	333/628 - (53%)	Gaps:	49/628 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NQAYVGSLNASTISIPGAYKPNESSNGKK--------TLSE-----GSGSAPPPGHGDSPSGV-- 65
            ||.|....:..:::..|.    .|::|:|        |.:|     ...:.||.|..|..|.:
  Fly   266 NQIYSDVTSVRSLASIGI----GSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDM 326

  Fly    66 --EAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVY 128
              |..|...::..|.|.::|:::||..|||||||||||:...::|||.|::||.|:|.:...|:.
  Fly   327 SDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLL 391

  Fly   129 YLEMLLGQFSSRGSV-KVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWS 192
            ::|:.:||::.||.: .:....|:.:|.|...|:.:.:::|||:.::..::.||..||...:||.
  Fly   392 FMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWI 456

  Fly   193 YCREEWGTECLDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPS---WSLAL 254
            .|...|.|.  |....:.....:.|....||.|.|| |.|.:|:    |..|:.||.   |.|..
  Fly   457 DCNNRWNTP--DCWVPQRKGINASAPDTSRTPSEEF-FENKVLQ----ISGGLEYPGMMRWELFA 514

  Fly   255 ALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLE 319
            .|..||:::....:|.:|||.|..||.|.||:|::::|:|||:||.||.:|:.:|.||:|.:|..
  Fly   515 CLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKN 579

  Fly   320 PQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLA 384
            ..||..|.:|.|.||.|.||::|.:||||::.:||.||...|:.::..||||.|:..|..|||||
  Fly   580 ANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLA 644

  Fly   385 YENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIK 449
            .|.| |::..|:..|||:.|:.||.|:||..: .||::|:||.||..||:.|...:...:.|.|:
  Fly   645 LEQN-TNVRDVIGDGPGMIFVVYPQAMAKMPY-AQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQ 707

  Fly   450 DQFGHLKNW---------TVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELV 505
            |.|   ..|         .||:.:.::....|:..|..||.:...|:|::..:...:.||..:::
  Fly   708 DGF---PRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMI 769

  Fly   506 TIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKD--YTYQSG 568
            .|||.||..||.::|:.|.|...|.|.|.||.|:.|.|:..|.:.:|:.|....|.:  |||...
  Fly   770 AIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDW 834

  Fly   569 VYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLGLWARIRKAFEP 611
            .|..||..::|.:..:..:|:....:..... .|.|||....|
  Fly   835 AYGIGWMFASFSLICIPGYAVINFLRSSGDT-FWERIRNTLRP 876

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	178/489 (36%)
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	193/551 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850