DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and F56F4.3

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_491770.3	Gene:	F56F4.3 / 186398	WormBaseID:	WBGene00018980	Length:	701	Species:	Caenorhabditis elegans

Alignment Length:	759	Identity:	168/759 - (22%)
Similarity:	275/759 - (36%)	Gaps:	229/759 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 STISIPGAYKPN---ESSNGKKTL-----------------------SEGSGSAP---------- 54
            ||...|...|.|   |:|..||.|                       :|.|...|
Worm     8 STPEDPKVKKENDTKENSPEKKLLQEEIEYNIVYGYDRKKKKKRMDSTESSSENPDGIEKFDNDE 72

  Fly    55 -----PPGHGD-SPSGVEA-------GQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALE 106
                 |.|:.: :||.:||       |.....|.|....:..|:||:.|   |.|...|......
Worm    73 ELAISPTGNPNLNPSKIEAEELEQEIGSRNISRPSTYRQLSLLLSCVTL---LKNNMVFIECFFN 134

  Fly   107 NGGGAFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYY 170
            :||..|.:||.|:|.::|.|:...|:.|.||||.....::. .:|::.||.: .:|...|:.|.|
Worm   135 HGGVYFFVPYFIILFVLGVPMAIFELSLAQFSSIPMNGMFTRMAPMLGGIPW-LILCLRIIYTVY 198

  Fly   171 ATLMALTLRYFVDSFYPTLP----WSYCREEWGTECLDSGPQEASRATSLAGSG-------VRTT 224
            .......|.|...||...:.    |.:|.:..|..|.|  |..:.:......:|       :|..
Worm   199 IAFDPRFLLYAYKSFVTVITGNMNWIHCDDYKGVRCFD--PTWSCKINEFRLNGECVKDVHIRKL 261

  Fly   225 SAE------FYFTNIILREKASID----------DGIGYPSWSLALALAVAWIVIAG-IMFKGVK 272
            :.:      .||.   |||...|.          :|:......||   |:.:::||| |.:||.:
Worm   262 AQQQDYGLLTYFG---LREYRLISIIPSQIYKEINGLDIMDNILA---ALVFLLIAGFITYKGHR 320

  Fly   273 SSGKASYFLALFPYVVML--VLLV---------------------------------RALTLPGA 302
            .....:.|....|.:.|:  |:||                                 ..:|:...
Worm   321 FFASLAGFFVFLPILGMIPAVILVYYDVGSRKKHFFNQILKNNDITKIFELSAWLNAARVTVKTV 385

  Fly   303 F--DGVLYFL--RPQW-HKLLEPQVWYAAVTQVFFSLAICFG--------NIIMYASYNRFGHNI 354
            :  ||.|..|  |..: |..::..|..|| :...:.|.:|||        |.|:|.    |...:
Worm   386 YIADGTLMALGSRADFRHNFIKDAVLLAA-SGATYRLLLCFGILPILYVANDILYP----FAKTV 445

  Fly   355 YRDANIVT--TLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWL 417
            |...::|.  .::.|.|.|....|.||...:     |..:.:::.|....||::|  .:..|:.|
Worm   446 YARGDLVQFHAIELFFSALPSYAIPGISPTV-----TFFVYAMLYGTINFAFVAY--QVITFEML 503

  Fly   418 PQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHLKNWTVVVGIAIVGYFLGLLY--ITPGG 480
            ......||..:|::.  ..:|.:...|:||           |:::.:    |.|.|.|  :..|.
Worm   504 INALHHLFPRLLYLK--QKSVRICIIMATV-----------TLLLFL----YILSLPYKQLAVGY 551

  Fly   481 QFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLC---------RDVEFMIGIKTSLYYRICW 536
            |..|.:.||  |..:.......:|::::.:||.|||.         ..|.:.:..|..::..:.|
Worm   552 QKELAIDDY--VVGLVSTTVFIQLISVSIVYGYKRLLINFLTMLKHHPVTYKLVEKCRVFLYVMW 614

  Fly   537 AVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAV------RKQ 595
            |...|:..|..:...:|    .||:         ::.|.|       ||:.||.|:      ||.
Worm   615 AFFLPISCLVSICSIIV----KKYQ---------IYHWPL-------VLYAAISALPLIYLARKL 659

  Fly   596 PSHLGLWARIRKAF----EPLPNWGPSDPQTLKRYQLFVQEGNA 635
            ..::     :||.|    .....|.|::            ||:|
Worm   660 TMYI-----MRKEFVSGLSQTHRWQPAN------------EGHA 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	127/566 (22%)
F56F4.3	NP_491770.3	SLC5-6-like_sbd	73..620	CDD:382020	133/589 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810